IR@PKUHSC  > 北京大学第二临床医学院
学科主题临床医学
Effect of Modified Formula Radix Hedysari on the Amplification Effect during Peripheral Nerve Regeneration
Wang, Zhi Yong; Zhang, Pei Xun; Han, Na; Kou, Yu Hui; Yin, Xiao Feng; Jiang, Bao Guo
刊名EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE
2013
DOI10.1155/2013/647982
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Integrative & Complementary Medicine
研究领域[WOS]Integrative & Complementary Medicine
关键词[WOS]GROWTH-FACTOR DELIVERY ; SPINAL-CORD ; AXON GROWTH ; INJURY
英文摘要

Many studies have demonstrated a compensatory amplification phenomenon during nerve regeneration. When a relatively fine nerve is used as a donor to connect to a distal nerve after transection, the donor nerve regenerates more collaterals than its own fibers, which extend to the distal stump, grow into distal endoneurial tubes, and finally reach and dominate the target organs. This is known as the amplification phenomenon. In this study, we investigated the amplification phenomenon in rats treated with Modified Formula Radix Hedysari (MFRH) as adjuvant therapy for 12 weeks. The rats were divided into three groups at random (six animals in each group). In the model group and the treatment group, the proximal common peroneal nerve was used as a donor nerve to connect to the distal tibial nerve. Rats in the normal group did not undergo surgery. After surgery, the treatment group was administered MFRH as systemic therapy, while the model group and the normal group were not given treatment. The results demonstrated that the nerve conduction velocity, the fiber diameter, the axon diameter, the number of regenerating nerve fibers, and the amplification ratio were better in the treatment group than in the model group, suggesting that MFRH promoted the nerve amplification effect.

语种英语
WOS记录号WOS:000315908600001
引用统计
被引频次:4[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/60809
专题北京大学第二临床医学院
作者单位Peking Univ, Peoples Hosp, Dept Trauma & Orthopead, Beijing 100044, Peoples R China
推荐引用方式
GB/T 7714
Wang, Zhi Yong,Zhang, Pei Xun,Han, Na,et al. Effect of Modified Formula Radix Hedysari on the Amplification Effect during Peripheral Nerve Regeneration[J]. EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE,2013.
APA Wang, Zhi Yong,Zhang, Pei Xun,Han, Na,Kou, Yu Hui,Yin, Xiao Feng,&Jiang, Bao Guo.(2013).Effect of Modified Formula Radix Hedysari on the Amplification Effect during Peripheral Nerve Regeneration.EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE.
MLA Wang, Zhi Yong,et al."Effect of Modified Formula Radix Hedysari on the Amplification Effect during Peripheral Nerve Regeneration".EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE (2013).
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