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学科主题: 临床医学
题名:
A comparison of NBI and WLI cystoscopy in detecting non-muscle-invasive bladder cancer: A prospective, randomized and multi-center study
作者: Ye, Zhangqun1; Hu, Jia1; Song, Xiaodong1; Li, Fan1; Zhao, Xuetao2; Chen, Shan3; Wang, Xiaofeng4; He, Dalin5; Fan, Jinhai5; Ye, Dingwei6; Xing, Jinchun7; Pan, Tiejun8; Wang, Dongwen9
刊名: SCIENTIFIC REPORTS
发表日期: 2015-06-05
DOI: 10.1038/srep10905
卷: 5
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Multidisciplinary Sciences
研究领域[WOS]: Science & Technology - Other Topics
关键词[WOS]: BAND IMAGING CYSTOSCOPY ; MANAGEMENT ; TUMORS
英文摘要:

Several single-center studies have investigated whether narrow-band imaging (NBI) cystoscopy is more effective in detecting primary and recurrent non-muscle invasive bladder cancer (NMIBC) compared with white-light imaging (WLI) cystoscopy. In this study, we further evaluated the diagnostic value of NBI cystoscopy compared with WLI cystoscopy for primary NMIBC in a multi-center study. Suspected bladder cancer patients from 8 research centers received both NBI and WLI. Two experienced doctors in each center were responsible for the NBI and WLI assessments, respectively. The number of tumors and position of each tumor were recorded, and suspicious tissues were clamped and histologically examined. The sensitivity, specificity, and false-positive rate of NBI and WLI were evaluated. Of the 384 patients, 78 had a confirmed urothelial carcinoma (UC). The sensitivities of NBI and WLI were 97.70%, and 66.67%, respectively (P < 0.0001); the specificities were 50% and 25%, respectively; and the false positive rates were 50% and 75%, respectively. Based on 300 valid biopsy specimens, the NBI and WLI sensitivities were 98.80% and 75.45%, respectively (P < 0.0001). These results suggest that NBI has a high sensitivity and has superior early bladder tumor and carcinoma in situ (CIS) detection rates compared with WLI cystoscopy.

语种: 英语
WOS记录号: WOS:000355864500001
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/60817
Appears in Collections:北京大学第二临床医学院_泌尿外科_期刊论文

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作者单位: 1.Huazhong Univ Sci & Technol, Tongji Hosp, Tongji Med Coll, Dept Urol, Wuhan 430030, Peoples R China
2.Fourth Hosp Wuhan, Dept Urol, Wuhan 430030, Peoples R China
3.Tongren Hosp, Dept Urol, Beijing 100730, Peoples R China
4.Peking Univ, Peoples Hosp, Dept Urol, Beijing 100044, Peoples R China
5.Xi An Jiao Tong Univ, Affiliated Hosp 1, Dept Urol, Xian 710061, Peoples R China
6.Fudan Univ, Canc Hosp, Dept Urol, Shanghai 200032, Peoples R China
7.Xiamen Univ, Affiliated Hosp 1, Dept Urol, Xiamen 361003, Peoples R China
8.Wuhan Gen Hosp Guangzhou Mil Reg, Dept Urol, Wuhan 430000, Peoples R China
9.Shanxi Med Univ, Affiliated Hosp 1, Dept Urol, Taiyuan 030001, Shanxi, Peoples R China

Recommended Citation:
Ye, Zhangqun,Hu, Jia,Song, Xiaodong,et al. A comparison of NBI and WLI cystoscopy in detecting non-muscle-invasive bladder cancer: A prospective, randomized and multi-center study[J]. SCIENTIFIC REPORTS,2015,5.
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