IR@PKUHSC  > 北京大学第二临床医学院  > 泌尿外科
学科主题临床医学
A comparison of NBI and WLI cystoscopy in detecting non-muscle-invasive bladder cancer: A prospective, randomized and multi-center study
Ye, Zhangqun1; Hu, Jia1; Song, Xiaodong1; Li, Fan1; Zhao, Xuetao2; Chen, Shan3; Wang, Xiaofeng4; He, Dalin5; Fan, Jinhai5; Ye, Dingwei6; Xing, Jinchun7; Pan, Tiejun8; Wang, Dongwen9
刊名SCIENTIFIC REPORTS
2015-06-05
DOI10.1038/srep10905
5
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Multidisciplinary Sciences
研究领域[WOS]Science & Technology - Other Topics
关键词[WOS]BAND IMAGING CYSTOSCOPY ; MANAGEMENT ; TUMORS
英文摘要

Several single-center studies have investigated whether narrow-band imaging (NBI) cystoscopy is more effective in detecting primary and recurrent non-muscle invasive bladder cancer (NMIBC) compared with white-light imaging (WLI) cystoscopy. In this study, we further evaluated the diagnostic value of NBI cystoscopy compared with WLI cystoscopy for primary NMIBC in a multi-center study. Suspected bladder cancer patients from 8 research centers received both NBI and WLI. Two experienced doctors in each center were responsible for the NBI and WLI assessments, respectively. The number of tumors and position of each tumor were recorded, and suspicious tissues were clamped and histologically examined. The sensitivity, specificity, and false-positive rate of NBI and WLI were evaluated. Of the 384 patients, 78 had a confirmed urothelial carcinoma (UC). The sensitivities of NBI and WLI were 97.70%, and 66.67%, respectively (P < 0.0001); the specificities were 50% and 25%, respectively; and the false positive rates were 50% and 75%, respectively. Based on 300 valid biopsy specimens, the NBI and WLI sensitivities were 98.80% and 75.45%, respectively (P < 0.0001). These results suggest that NBI has a high sensitivity and has superior early bladder tumor and carcinoma in situ (CIS) detection rates compared with WLI cystoscopy.

语种英语
WOS记录号WOS:000355864500001
引用统计
被引频次:4[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/60817
专题北京大学第二临床医学院_泌尿外科
作者单位1.Huazhong Univ Sci & Technol, Tongji Hosp, Tongji Med Coll, Dept Urol, Wuhan 430030, Peoples R China
2.Fourth Hosp Wuhan, Dept Urol, Wuhan 430030, Peoples R China
3.Tongren Hosp, Dept Urol, Beijing 100730, Peoples R China
4.Peking Univ, Peoples Hosp, Dept Urol, Beijing 100044, Peoples R China
5.Xi An Jiao Tong Univ, Affiliated Hosp 1, Dept Urol, Xian 710061, Peoples R China
6.Fudan Univ, Canc Hosp, Dept Urol, Shanghai 200032, Peoples R China
7.Xiamen Univ, Affiliated Hosp 1, Dept Urol, Xiamen 361003, Peoples R China
8.Wuhan Gen Hosp Guangzhou Mil Reg, Dept Urol, Wuhan 430000, Peoples R China
9.Shanxi Med Univ, Affiliated Hosp 1, Dept Urol, Taiyuan 030001, Shanxi, Peoples R China
推荐引用方式
GB/T 7714
Ye, Zhangqun,Hu, Jia,Song, Xiaodong,et al. A comparison of NBI and WLI cystoscopy in detecting non-muscle-invasive bladder cancer: A prospective, randomized and multi-center study[J]. SCIENTIFIC REPORTS,2015,5.
APA Ye, Zhangqun.,Hu, Jia.,Song, Xiaodong.,Li, Fan.,Zhao, Xuetao.,...&Wang, Dongwen.(2015).A comparison of NBI and WLI cystoscopy in detecting non-muscle-invasive bladder cancer: A prospective, randomized and multi-center study.SCIENTIFIC REPORTS,5.
MLA Ye, Zhangqun,et al."A comparison of NBI and WLI cystoscopy in detecting non-muscle-invasive bladder cancer: A prospective, randomized and multi-center study".SCIENTIFIC REPORTS 5(2015).
条目包含的文件
条目无相关文件。
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Ye, Zhangqun]的文章
[Hu, Jia]的文章
[Song, Xiaodong]的文章
百度学术
百度学术中相似的文章
[Ye, Zhangqun]的文章
[Hu, Jia]的文章
[Song, Xiaodong]的文章
必应学术
必应学术中相似的文章
[Ye, Zhangqun]的文章
[Hu, Jia]的文章
[Song, Xiaodong]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。