IR@PKUHSC  > 北京大学药学院
学科主题药学
Sialylation reactions with N,N-dibenzylthiosialoside donor
Wang, Yue; Xu, Fei-Fei; Ye, Xin-Shan1
关键词Sialylation Stereoselectivity Carbohydrate Synthetic method
刊名TETRAHEDRON LETTERS
2012-07-11
DOI10.1016/j.tetlet.2012.05.024
53期:28页:3658-3662
收录类别SCI ; IC
文章类型Article
WOS标题词Science & Technology
类目[WOS]Chemistry, Organic
资助者National High Technology Research and Development Program of China ; National Basic Research Program of China (973 Program) ; National High Technology Research and Development Program of China ; National Basic Research Program of China (973 Program)
研究领域[WOS]Chemistry
关键词[WOS]ALPHA-SELECTIVE SIALYLATIONS ; N-ACETYLNEURAMINIC ACID ; ACETYL-NEURAMINIC ACID ; CELL-SURFACE GLYCANS ; ONE-POT SYNTHESIS ; SIALIC-ACID ; STEREOSELECTIVE-SYNTHESIS ; GLYCOSYL DONOR ; O-SIALYLATION ; DERIVATIVES
英文摘要

A new sialyl donor, N,N-dibenzyl-protected p-toluenethiosialoside, was synthesized and its sialylation reaction was investigated. This reaction proceeded in a preactivation manner and preferred to provide beta-anomeric coupling products. The beta-selectivity was rationalized based on the assumption that N,N-dibenzylamino group could serve as an oriented group to activate the hydroxyl group of acceptor from beta-face. (C) 2012 Elsevier Ltd. All rights reserved.

语种英语
所属项目编号2012AA021504 ; 2012CB822100
资助者National High Technology Research and Development Program of China ; National Basic Research Program of China (973 Program) ; National High Technology Research and Development Program of China ; National Basic Research Program of China (973 Program)
WOS记录号WOS:000305856100029
引用统计
被引频次:5[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/60820
专题北京大学药学院
作者单位1.Peking Univ, State Key Lab Nat & Biomimet Drugs, Beijing 100191, Peoples R China
2.Peking Univ, Sch Pharmaceut Sci, Beijing 100191, Peoples R China
推荐引用方式
GB/T 7714
Wang, Yue,Xu, Fei-Fei,Ye, Xin-Shan. Sialylation reactions with N,N-dibenzylthiosialoside donor[J]. TETRAHEDRON LETTERS,2012,53(28):3658-3662.
APA Wang, Yue,Xu, Fei-Fei,&Ye, Xin-Shan.(2012).Sialylation reactions with N,N-dibenzylthiosialoside donor.TETRAHEDRON LETTERS,53(28),3658-3662.
MLA Wang, Yue,et al."Sialylation reactions with N,N-dibenzylthiosialoside donor".TETRAHEDRON LETTERS 53.28(2012):3658-3662.
条目包含的文件
条目无相关文件。
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Wang, Yue]的文章
[Xu, Fei-Fei]的文章
[Ye, Xin-Shan]的文章
百度学术
百度学术中相似的文章
[Wang, Yue]的文章
[Xu, Fei-Fei]的文章
[Ye, Xin-Shan]的文章
必应学术
必应学术中相似的文章
[Wang, Yue]的文章
[Xu, Fei-Fei]的文章
[Ye, Xin-Shan]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。