IR@PKUHSC  > 北京大学公共卫生学院
学科主题公共卫生
Passive smoking, Cyp1A1 gene polymorphism and dysmenorrhea
Liu, Hong; Yang, Fan; Li, Zhiping; Chen, Changzhong; Fang, Zhian; Wang, Lihua; Hu, Yonghua; Chen, Dafang
关键词cytochrome P-450CYP1A1 dysmenorrhea polymorphism genetic tobacco smoke pollution
刊名REPRODUCTIVE TOXICOLOGY
2007-07-01
DOI10.1016/j.reprotox.2007.04.069
24期:1页:114-119
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Reproductive Biology ; Toxicology
研究领域[WOS]Reproductive Biology ; Toxicology
关键词[WOS]CIGARETTE-SMOKING ; TOBACCO-SMOKE ; YOUNG-WOMEN ; RISK ; ASSOCIATION ; SEVERITY ; WEIGHT ; CANCER ; PAIN ; DNA
英文摘要

Objective: This study investigated whether the association between passive smoking exposure and dysmenorrhea is modified by two susceptibility genes, CYP1A1 MspI and CYP1A1HincII.

Methods: This report includes 1645 (1124 no dysmenorrhea, 521 dysmenorrhea) nonsmoking and nondrinking newly wed female workers at Anqing, China between June 1997 and June 2000. Multiple logistic regression models were used to estimate the associations of passive smoking exposure and genetic susceptibility with dysmenorrhea, adjusting for perceived stress.

Results: When stratified by women genotype, the adjusted OR of dysmenorrhea was 1.6 (95%CI = 1.3-2.1) for passive smoking group with Ile/Ile462 genotype, and 1.5 (95%CI = 1.1-2.1) with C/C6235 genotype, compared to nonpassive smoking group, respectively. The data further showed that there was a significant combined effect between passive smoking and the CYP1A1 MspI C/C6235 and HincII Ile/Ile462 genotype (OR = 2.6, 95%CI = 1.3-5.2).

Conclusion: CYP1A1 MspI and HincII genotypes modified the association between passive smoking and dysmenorrhea. (c) 2007 Elsevier Inc. All rights reserved.

语种英语
WOS记录号WOS:000248775200012
引用统计
被引频次:3[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/60840
专题北京大学公共卫生学院
作者单位1.Peking Univ, Hlth Sci Ctr, Dept Epidemiol & Biostat, Sch Publ Hlth, Beijing 100083, Peoples R China
2.Harvard Univ, Sch Med, Brigham & Womens Hosp, Boston, MA 02115 USA
推荐引用方式
GB/T 7714
Liu, Hong,Yang, Fan,Li, Zhiping,et al. Passive smoking, Cyp1A1 gene polymorphism and dysmenorrhea[J]. REPRODUCTIVE TOXICOLOGY,2007,24(1):114-119.
APA Liu, Hong.,Yang, Fan.,Li, Zhiping.,Chen, Changzhong.,Fang, Zhian.,...&Chen, Dafang.(2007).Passive smoking, Cyp1A1 gene polymorphism and dysmenorrhea.REPRODUCTIVE TOXICOLOGY,24(1),114-119.
MLA Liu, Hong,et al."Passive smoking, Cyp1A1 gene polymorphism and dysmenorrhea".REPRODUCTIVE TOXICOLOGY 24.1(2007):114-119.
条目包含的文件
条目无相关文件。
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Liu, Hong]的文章
[Yang, Fan]的文章
[Li, Zhiping]的文章
百度学术
百度学术中相似的文章
[Liu, Hong]的文章
[Yang, Fan]的文章
[Li, Zhiping]的文章
必应学术
必应学术中相似的文章
[Liu, Hong]的文章
[Yang, Fan]的文章
[Li, Zhiping]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。