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Differences in Baseline Dark and the Dark-to-Light Changes in Anterior Chamber Angle Parameters in Whites and Ethnic Chinese
Wang, Dandan1,2; Chiu, Cynthia1; He, Mingguang2; Wu, Lingling3; Kao, Andrew1; Lin, Shan1
刊名INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
2011-12-01
DOI10.1167/iovs.11-8470
52期:13页:9404-9410
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Ophthalmology
研究领域[WOS]Ophthalmology
关键词[WOS]OPTICAL COHERENCE TOMOGRAPHY ; CLOSURE GLAUCOMA ; LIWAN EYE ; IRIS ; POPULATION ; GONIOSCOPY ; SUSPECTS ; BIOMETRY ; PEOPLE ; IMAGES
英文摘要

PURPOSE. To assess the anterior chamber drainage angle width in the dark and the dark-to-light change (Delta) between Caucasians and Chinese aged 40 years and older.

METHODS. The study groups comprised four age-and sexmatched cohorts: American Caucasians, American Chinese, southern mainland Chinese, and northern mainland Chinese. Anterior segment optical coherence tomography (ASOCT) images of the anterior chamber angles were obtained under both light and dark conditions. The parameters analyzed included angle opening distance (AOD), angle recess area (ARA), and trabecular-iris space area (TISA).

RESULTS. Data were obtained from 121, 124, 121, and 120 participants who were American Caucasians, American Chinese, and southern and northern mainland Chinese, respectively. In a multiple linear regression analysis, adjusted for age, sex, refractive status, pupil size, lens location, and anterior chamber depth (ACD) and width (ACW), the ethnic Chinese had significantly smaller ARAs (regression coefficient, beta = -0.06, P < 0.001) and TISAs (beta = -0.01, P = 0.039), as well as greater Delta AODs (beta = 0.03, P = 0.009) and Delta TISAs (beta = 0.02, P = 0.029) than did the Caucasians. For the dark-to-light change analysis, the independent associations between angle width and iris thickness (IT) and iris curvature (ICurv) were identified only in the Chinese.

CONCLUSIONS. Compared with the Caucasians, the ethnic Chinese had smaller ARA and TISA, but greater dark-to-light changes in AOD and TISA, independent of refractive status and overall ocular anterior segment dimensions. (Invest Ophthalmol Vis Sci. 2011; 52: 9404-9410) DOI: 10.1167/iovs.11-8470

语种英语
WOS记录号WOS:000298628200018
项目编号EY002161
资助机构George and Rosalie Hearst Foreign Fellowship ; That Man May See, Inc. ; Research to Prevent Blindness ; National Eye Institute Core
引用统计
被引频次:10[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/60851
专题北京大学第三临床医学院_眼科
作者单位1.Univ Calif San Francisco, Dept Ophthalmol, San Francisco, CA USA
2.Sun Yat Sen Univ, Zhongshan Ophthalm Ctr, State Key Lab Ophthalmol, Guangzhou 510275, Guangdong, Peoples R China
3.Peking Univ, Hosp 3, Ctr Eye, Beijing 100871, Peoples R China
推荐引用方式
GB/T 7714
Wang, Dandan,Chiu, Cynthia,He, Mingguang,et al. Differences in Baseline Dark and the Dark-to-Light Changes in Anterior Chamber Angle Parameters in Whites and Ethnic Chinese[J]. INVESTIGATIVE OPHTHALMOLOGY &amp; VISUAL SCIENCE,2011,52(13):9404-9410.
APA Wang, Dandan,Chiu, Cynthia,He, Mingguang,Wu, Lingling,Kao, Andrew,&Lin, Shan.(2011).Differences in Baseline Dark and the Dark-to-Light Changes in Anterior Chamber Angle Parameters in Whites and Ethnic Chinese.INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE,52(13),9404-9410.
MLA Wang, Dandan,et al."Differences in Baseline Dark and the Dark-to-Light Changes in Anterior Chamber Angle Parameters in Whites and Ethnic Chinese".INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 52.13(2011):9404-9410.
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