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Bridging peripheral nerves using a deacetyl chitin conduit combined with short-term electrical stimulation
Zhang, Zhongli1; Li, Xin2; Zuo, Songjie3; Xin, Jie1; Zhang, Peixun4
关键词nerve regeneration peripheral nerve injury deacetyl chitin conduit electrical stimulation NSFC grant neural regeneration
刊名NEURAL REGENERATION RESEARCH
2014-05-01
DOI10.4103/1673-5374.133168
9期:10页:1075-1078
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Cell Biology ; Neurosciences
研究领域[WOS]Cell Biology ; Neurosciences & Neurology
关键词[WOS]FUNCTIONAL RECOVERY ; SMALL-GAP ; INJURY ; OUTGROWTH
英文摘要

Previous studies have demonstrated that deacetyl chitin conduit nerve bridging or electrical stimulation can effectively promote the regeneration of the injured peripheral nerve. We hypothesized that the combination of these two approaches could result in enhanced regeneration. Rats with right sciatic nerve injury were subjected to deacetyl chitin conduit bridging combined with electrical stimulation (0.1 ms, 3 V, 20 Hz, for 1 hour). At 6 and 12 weeks after treatment, nerve conduction velocity, myelinated axon number, fiber diameter, axon diameter and the thickness of the myelin sheath in the stimulation group were better than in the non-stimulation group. The results indicate that deacetyl chitin conduit bridging combined with temporary electrical stimulation can promote peripheral nerve repair.

语种英语
WOS记录号WOS:000337068800013
引用统计
被引频次:3[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/60865
专题北京大学第二临床医学院
北京大学第二临床医学院_创伤骨科
作者单位1.Weifang Med Coll, Dept Physiol, Weifang, Shandong, Peoples R China
2.Weifang Peoples Hosp, Dept Traumat Orthoped, Weifang, Shandong, Peoples R China
3.Chinese Ctr Dis Prevent & Control, Natl Inst Radiol Protect, Beijing, Peoples R China
4.Peking Univ, Peoples Hosp, Dept Trauma & Orthoped, Beijing 100044, Peoples R China
推荐引用方式
GB/T 7714
Zhang, Zhongli,Li, Xin,Zuo, Songjie,et al. Bridging peripheral nerves using a deacetyl chitin conduit combined with short-term electrical stimulation[J]. NEURAL REGENERATION RESEARCH,2014,9(10):1075-1078.
APA Zhang, Zhongli,Li, Xin,Zuo, Songjie,Xin, Jie,&Zhang, Peixun.(2014).Bridging peripheral nerves using a deacetyl chitin conduit combined with short-term electrical stimulation.NEURAL REGENERATION RESEARCH,9(10),1075-1078.
MLA Zhang, Zhongli,et al."Bridging peripheral nerves using a deacetyl chitin conduit combined with short-term electrical stimulation".NEURAL REGENERATION RESEARCH 9.10(2014):1075-1078.
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