北京大学医学部机构知识库
Advanced  
IR@PKUHSC  > 北京大学深圳医院  > 病理科  > 期刊论文
学科主题: 临床医学
题名:
Desmoplastic small round cell tumor of the submandibular gland-a rare but distinctive primary salivary gland neoplasm
作者: Yin, Wei-Hua2; Guo, Shuang-Ping1; Yang, Hong-Yu2; Chan, John K. C.3
关键词: Salivary gland tumor ; Desmoplastic small round cell tumor ; Molecular analysis ; EWS/WT1 gene fusion
刊名: HUMAN PATHOLOGY
发表日期: 2010-03-01
DOI: 10.1016/j.humpath.2009.08.015
卷: 41, 期:3, 页:438-442
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Pathology
研究领域[WOS]: Pathology
关键词[WOS]: SPECTRUM
英文摘要:

Desmoplastic small round cell tumor is a highly aggressive neoplasm that generally involves the peritoneum and pelvis of young patients. Only rare cases occur outside the abdomen. We report a case presenting as a primary submandibular gland tumor in a 24-year-old man. Histologically, although there were irregular tumor islands lying in an abundant desmoplastic stroma, there were also areas comprising large cellular islands with scanty stroma in between, raising the differential diagnosis of various salivary gland carcinomas. The tumor cells were medium sized, with hyperchromatic nuclei and moderate amounts of cytoplasm. The diagnosis of desmoplastic small round cell tumor was confirmed by the presence of a polyphenotypic immunoprofile (positive for cytokeratin, desmin, and neuron-specific enolase) and the characteristic EWS-WT1 gene fusion. Although rare, desmoplastic small round cell tumor has to be considered in the differential diagnosis of poorly differentiated neoplasms of the salivary gland, especially in young patients. (C) 2010 Elsevier Inc. All rights reserved.

语种: 英语
WOS记录号: WOS:000276493700017
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/60878
Appears in Collections:北京大学深圳医院_病理科_期刊论文

Files in This Item:

There are no files associated with this item.


作者单位: 1.Fourth Mil Med Univ, Xi Jing Hosp, Dept Pathol, Xian 710032, Peoples R China
2.Queen Elizabeth Hosp, Dept Pathol, Hong Kong, Hong Kong, Peoples R China
3.Peking Univ, Shenzhen Hosp, Dept Pathol, Shenzhen 518001, Peoples R China

Recommended Citation:
Yin, Wei-Hua,Guo, Shuang-Ping,Yang, Hong-Yu,et al. Desmoplastic small round cell tumor of the submandibular gland-a rare but distinctive primary salivary gland neoplasm[J]. HUMAN PATHOLOGY,2010,41(3):438-442.
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[Yin, Wei-Hua]'s Articles
[Guo, Shuang-Ping]'s Articles
[Yang, Hong-Yu]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[Yin, Wei-Hua]‘s Articles
[Guo, Shuang-Ping]‘s Articles
[Yang, Hong-Yu]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit
所有评论 (0)
暂无评论
 
评注功能仅针对注册用户开放,请您登录
您对该条目有什么异议,请填写以下表单,管理员会尽快联系您。
内 容:
Email:  *
单位:
验证码:   刷新
您在IR的使用过程中有什么好的想法或者建议可以反馈给我们。
标 题:
 *
内 容:
Email:  *
验证码:   刷新

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Copyright © 2007-2017  北京大学医学部 - Feedback
Powered by CSpace