IR@PKUHSC  > 北京大学第三临床医学院  > 心血管内科
学科主题临床医学
The important role of catestatin in cardiac remodeling
Wu, Zheng; Zhu, Dan
关键词Apoptosis cardiac remodeling catestatin fibrosis hypertrophy
刊名BIOMARKERS
2014-12-01
DOI10.3109/1354750X.2014.950331
19期:8页:625-630
收录类别SCI
文章类型Review
WOS标题词Science & Technology
类目[WOS]Biotechnology & Applied Microbiology ; Toxicology
研究领域[WOS]Biotechnology & Applied Microbiology ; Toxicology
关键词[WOS]CHROMOGRANIN-A FRAGMENT ; RELEASE-INHIBITORY PEPTIDE ; ACUTE MYOCARDIAL-INFARCTION ; CATECHOLAMINE RELEASE ; NITRIC-OXIDE ; IN-VIVO ; HEART-FAILURE ; GROWTH-FACTOR ; MATRIX METALLOPROTEINASES ; CARDIOVASCULAR-DISEASE
英文摘要

Catestatin (CST) was first discovered as a potent non-competitive and reversible inhibitor of catecholamine secretion. Recent reports on plasma CST level in heart diseases suggested a cardioprotective role for this peptide. Given that cardiac remodeling is the dominant pathologic process in cardiac dysfunction, we propose that CST participates in the regulation of concern pathways and contributes to the inhibition of cardiac remodeling. In this minireview, the potential mechanism of cardiac remodeling involving CST will be discussed from three aspects: hypertrophy, fibrosis, and apoptosis.

语种英语
WOS记录号WOS:000345498100001
引用统计
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/60918
专题北京大学第三临床医学院_心血管内科
作者单位1.Peking Univ, Dept Cardiol, Hosp 3,Minist Hlth, Key Lab Cardiovasc Mol Biol & Regulatory Peptides, Beijing 100191, Peoples R China
2.Peking Univ, Dept Cardiol, Hosp 3, Key Lab Mol Cardiovasc Sci,Dept Cardiol, Beijing 100191, Peoples R China
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GB/T 7714
Wu, Zheng,Zhu, Dan. The important role of catestatin in cardiac remodeling[J]. BIOMARKERS,2014,19(8):625-630.
APA Wu, Zheng,&Zhu, Dan.(2014).The important role of catestatin in cardiac remodeling.BIOMARKERS,19(8),625-630.
MLA Wu, Zheng,et al."The important role of catestatin in cardiac remodeling".BIOMARKERS 19.8(2014):625-630.
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