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IR@PKUHSC  > 北京大学第三临床医学院  > 心血管内科  > 期刊论文
学科主题: 临床医学
题名:
The important role of catestatin in cardiac remodeling
作者: Wu, Zheng; Zhu, Dan
关键词: Apoptosis ; cardiac remodeling ; catestatin ; fibrosis ; hypertrophy
刊名: BIOMARKERS
发表日期: 2014-12-01
DOI: 10.3109/1354750X.2014.950331
卷: 19, 期:8, 页:625-630
收录类别: SCI
文章类型: Review
WOS标题词: Science & Technology
类目[WOS]: Biotechnology & Applied Microbiology ; Toxicology
研究领域[WOS]: Biotechnology & Applied Microbiology ; Toxicology
关键词[WOS]: CHROMOGRANIN-A FRAGMENT ; RELEASE-INHIBITORY PEPTIDE ; ACUTE MYOCARDIAL-INFARCTION ; CATECHOLAMINE RELEASE ; NITRIC-OXIDE ; IN-VIVO ; HEART-FAILURE ; GROWTH-FACTOR ; MATRIX METALLOPROTEINASES ; CARDIOVASCULAR-DISEASE
英文摘要:

Catestatin (CST) was first discovered as a potent non-competitive and reversible inhibitor of catecholamine secretion. Recent reports on plasma CST level in heart diseases suggested a cardioprotective role for this peptide. Given that cardiac remodeling is the dominant pathologic process in cardiac dysfunction, we propose that CST participates in the regulation of concern pathways and contributes to the inhibition of cardiac remodeling. In this minireview, the potential mechanism of cardiac remodeling involving CST will be discussed from three aspects: hypertrophy, fibrosis, and apoptosis.

语种: 英语
所属项目编号: 81200167 ; 20120001120131
项目资助者: National Natural Science Foundation of China ; Ph.D. Programs Foundation of the Ministry of Education of China
WOS记录号: WOS:000345498100001
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/60918
Appears in Collections:北京大学第三临床医学院_心血管内科_期刊论文

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作者单位: 1.Peking Univ, Dept Cardiol, Hosp 3,Minist Hlth, Key Lab Cardiovasc Mol Biol & Regulatory Peptides, Beijing 100191, Peoples R China
2.Peking Univ, Dept Cardiol, Hosp 3, Key Lab Mol Cardiovasc Sci,Dept Cardiol, Beijing 100191, Peoples R China

Recommended Citation:
Wu, Zheng,Zhu, Dan. The important role of catestatin in cardiac remodeling[J]. BIOMARKERS,2014,19(8):625-630.
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