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学科主题: 药学
题名:
Development of high-performance liquid chromatographic fingerprint for quality analysis of Hedysari Radix
作者: Liu, Yi1,2,3; Zhao, Yuying1,2; Chen, Hubiao4; Liang, Hong1,2; Zhang, Qingying1,2
关键词: Hedysarum polybotrys ; Hedysari Radix ; high-performance liquid chromatographic fingerprint ; quality analysis ; traditional Chinese medicine (TCM)
刊名: NATURAL PRODUCT RESEARCH
发表日期: 2013-08-01
DOI: 10.1080/14786419.2012.746341
卷: 27, 期:15, 页:1398-1403
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Chemistry, Applied ; Chemistry, Medicinal
研究领域[WOS]: Chemistry ; Pharmacology & Pharmacy
关键词[WOS]: HPLC ; FLAVONOIDS
英文摘要:

In this study, a simple, sensitive and reliable fingerprint analysis method by high-performance liquid chromatography coupled with diode array detection was developed for raw materials of Hedysari Radix, which is a famous traditional Chinese medicine and widely used as a restorative food. Then the developed method was subsequently applied to analyse 48 samples collected or purchased from different origins. Twenty-six common fingerprint peaks, including six definitely identified peaks, were found in total, and were involved for further characterisation and quality evaluation of Hedysari Radix. The chemical quality of commercial samples and samples collected in spring varied obviously, while those of the cultivated samples collected in autumn were relatively stable, indicating that it is better to harvest Hedysari Radix in autumn and that more attention should be paid to the standardisation of the process of harvesting, manufacturing and storage of Hedysari Radix.

语种: 英语
所属项目编号: 2009ZX09308-004 ; 21172008
项目资助者: project of Quality standards for traditional Chinese medicines and information system platform ; National Natural Science Foundation of China
WOS记录号: WOS:000323475400013
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/60924
Appears in Collections:北京大学药学院_期刊论文

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作者单位: 1.Natl Inst Food & Drug Control, Beijing 100050, Peoples R China
2.Peking Univ, Hlth Sci Ctr, Sch Pharmaceut Sci, State Key Lab Nat & Biomimet Drugs, Beijing 100191, Peoples R China
3.Peking Univ, Hlth Sci Ctr, Sch Pharmaceut Sci, Dept Nat Med, Beijing 100191, Peoples R China
4.Hong Kong Baptist Univ, Sch Chinese Med, Kowloon Tong, Hong Kong, Peoples R China

Recommended Citation:
Liu, Yi,Zhao, Yuying,Chen, Hubiao,et al. Development of high-performance liquid chromatographic fingerprint for quality analysis of Hedysari Radix[J]. NATURAL PRODUCT RESEARCH,2013,27(15):1398-1403.
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