IR@PKUHSC  > 北京大学第一临床医学院  > 血液内科
学科主题临床医学
Reactive Oxygen Species Alteration of Immune Cells in Local Residents at an Electronic Waste Recycling Site in Northern China
Li, Ran1,2; Yang, Qiaoyun1,2; Qiu, Xinghua1,2; Li, Keqiu3; Li, Guang3; Zhu, Ping4; Zhu, Tong1,2
刊名ENVIRONMENTAL SCIENCE & TECHNOLOGY
2013-04-02
DOI10.1021/es400027v
47期:7页:3344-3352
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Engineering, Environmental ; Environmental Sciences
研究领域[WOS]Engineering ; Environmental Sciences & Ecology
关键词[WOS]POLYBROMINATED DIPHENYL ETHERS ; POLYCHLORINATED-BIPHENYLS PCBS ; PERSISTENT ORGANIC POLLUTANTS ; DIBENZO-P-DIOXINS ; RESPIRATORY BURST ; EXPOSURE ; ACTIVATION ; MECHANISMS ; STRESS ; PBDES
英文摘要

The health effects of exposure to pollutants from electronic waste (e-waste) pose an important issue. In this study, we explored the association between oxidative stress and blood levels of e-waste-related pollutants. Blood samples were collected from individuals living in the proximity of an e-waste recycling site located in northern China, and pollutants, as well as reactive oxygen species (ROS), were measured in comparison to a reference population. The geometric mean concentrations of PCBs, dechlorane plus, and 2,2′,4,4′,5,5′-hexabromobiphenyl in plasma from the exposure group were 60.4, 9.0, and 0.55 ng g(-1) lipid, respectively, which were 2.2, 3.2, and 2.2 times higher than the corresponding measurement in the reference group. Correspondingly, ROS levels in white blood cells, including in neutrophil granulocytes, from the exposure group were significantly higher than in those from the reference group, suggesting potential ROS related health effects for residents at the e-waste site. In contrast, fewer ROS were generated in the respiratory burst of neutrophil granulocytes for the exposure group, indicating a depressed innate immune function for the individuals living at the e-waste site. These findings suggest a potential linkage between exposure to pollutants from e-waste recycling and both elevated oxidative stress and altered immune function.

语种英语
WOS记录号WOS:000317173100043
引用统计
被引频次:20[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/60977
专题北京大学第一临床医学院_血液内科
作者单位1.Peking Univ, Coll Environm Sci & Engn, State Key Joint Lab Environm Simulat & Pollut Con, Beijing 100871, Peoples R China
2.Peking Univ, Ctr Environm & Hlth, Beijing 100871, Peoples R China
3.Tianjin Med Univ, Basic Med Coll, Tianjin 300070, Peoples R China
4.Peking Univ, Hosp 1, Dept Hematol, Beijing 100034, Peoples R China
推荐引用方式
GB/T 7714
Li, Ran,Yang, Qiaoyun,Qiu, Xinghua,et al. Reactive Oxygen Species Alteration of Immune Cells in Local Residents at an Electronic Waste Recycling Site in Northern China[J]. ENVIRONMENTAL SCIENCE & TECHNOLOGY,2013,47(7):3344-3352.
APA Li, Ran.,Yang, Qiaoyun.,Qiu, Xinghua.,Li, Keqiu.,Li, Guang.,...&Zhu, Tong.(2013).Reactive Oxygen Species Alteration of Immune Cells in Local Residents at an Electronic Waste Recycling Site in Northern China.ENVIRONMENTAL SCIENCE & TECHNOLOGY,47(7),3344-3352.
MLA Li, Ran,et al."Reactive Oxygen Species Alteration of Immune Cells in Local Residents at an Electronic Waste Recycling Site in Northern China".ENVIRONMENTAL SCIENCE & TECHNOLOGY 47.7(2013):3344-3352.
条目包含的文件
条目无相关文件。
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Li, Ran]的文章
[Yang, Qiaoyun]的文章
[Qiu, Xinghua]的文章
百度学术
百度学术中相似的文章
[Li, Ran]的文章
[Yang, Qiaoyun]的文章
[Qiu, Xinghua]的文章
必应学术
必应学术中相似的文章
[Li, Ran]的文章
[Yang, Qiaoyun]的文章
[Qiu, Xinghua]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。