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Growth differentiation factor 15 in different stages of heart failure: potential screening implications
Wang, Fangfang1,2; Guo, Yanhong1,2; Yu, Haiyi1,2; Zheng, Lingbing1,2; Mi, Lin1,2; Gao, Wei1,2
关键词Growth differentiation factor 15 heart failure biomarkers
刊名BIOMARKERS
2010-12-01
DOI10.3109/1354750X.2010.510580
15期:8页:671-676
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Biotechnology & Applied Microbiology ; Toxicology
研究领域[WOS]Biotechnology & Applied Microbiology ; Toxicology
关键词[WOS]LEFT-VENTRICULAR HYPERTROPHY ; NATRIURETIC PEPTIDES ; SYSTOLIC DYSFUNCTION ; BETA SUPERFAMILY ; MANAGEMENT ; GUIDELINES ; HYPERTENSION ; ASSOCIATION ; DIAGNOSIS ; PLASMA
英文摘要

Identification of individuals in the early stage of heart failure (HF) may allow earlier initiation of disease-modifying treatment. We evaluated concentrations of the growth differentiation factor (GDF)-15at different stages and its potential screening value in 208 subjects. Plasma GDF-15 was measured by using an enzyme-linked immunosorbent assay. GDF-15 was positively correlated with the stages of HF (r=0.804, p < 0.001). In distinguishing patients with stage B HF, the area under the curve was 0.873 (p < 0.001). These findings indicate that GDF-15 concentration was elevated with the progressing stages of HFand might have potential screening implications for stage B HF.

语种英语
WOS记录号WOS:000284218800003
项目编号2007cb512107
资助机构National Basic Research Program of the PR China
引用统计
被引频次:21[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/60996
专题北京大学第三临床医学院
北京大学医学部管理机构_医学部
北京大学第三临床医学院_心血管内科
作者单位1.Minist Educ, Key Lab Mol, Beijing, Peoples R China
2.Peking Univ, Hlth Sci Ctr, Hosp 3, Beijing 100871, Peoples R China
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GB/T 7714
Wang, Fangfang,Guo, Yanhong,Yu, Haiyi,et al. Growth differentiation factor 15 in different stages of heart failure: potential screening implications[J]. BIOMARKERS,2010,15(8):671-676.
APA Wang, Fangfang,Guo, Yanhong,Yu, Haiyi,Zheng, Lingbing,Mi, Lin,&Gao, Wei.(2010).Growth differentiation factor 15 in different stages of heart failure: potential screening implications.BIOMARKERS,15(8),671-676.
MLA Wang, Fangfang,et al."Growth differentiation factor 15 in different stages of heart failure: potential screening implications".BIOMARKERS 15.8(2010):671-676.
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