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学科主题: 临床医学
题名:
CT-guided iodine-125 seed permanent implantation for recurrent head and neck cancers
作者: Jiang, Yu L.1; Meng, Na1; Wang, Jun J.1; Jiang, Ping1; Yuan, Hui Sh2; Liu, Chen2; Qu, Ang1; Yang, Rui J.1
刊名: RADIATION ONCOLOGY
发表日期: 2010-07-30
DOI: 10.1186/1748-717X-5-68
卷: 5
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Oncology ; Radiology, Nuclear Medicine & Medical Imaging
研究领域[WOS]: Oncology ; Radiology, Nuclear Medicine & Medical Imaging
关键词[WOS]: SQUAMOUS-CELL CANCER ; LIVER MALIGNANCIES ; RADIATION-THERAPY ; CAROTID-ARTERY ; I125 IMPLANTS ; BRACHYTHERAPY ; REIRRADIATION ; CARCINOMA ; TUMORS ; TONGUE
英文摘要:

Background: To investigate the feasibility, and safety of (125)I seed permanent implantation for recurrent head and neck carcinoma under CT-guidance.

Results: A retrospective study on 14 patients with recurrent head and neck cancers undergone (125)I seed implantation with different seed activities. The post-plan showed that the actuarial D90 of (125)I seeds ranged from 90 to 218 Gy (median, 157.5 Gy). The follow-up was 3 to 60 months (median, 13 months). The median local control was 18 months (95% CI, 6.1-29.9 months), and the 1-, 2-, 3-, and 5-year local controls were 52%, 39%, 39%, and 39%, respectively. The 1-, 2-, 3-, and 5-survival rates were 65%, 39%, 39% and 39%, respectively, with a median survival time of 20 months (95% CI, 8.7-31.3 months). Of all patients, 28.6% (4/14) died of local recurrence, 7.1% (1/14) died of metastases, one patient died of hepatocirrhosis, and 8 patients are still alive to the date of data analysis.

Conclusion: CT-guided (125)I seed implantation is feasible and safe as a salvage or palliative treatment for patients with recurrent head and neck cancers.

语种: 英语
所属项目编号: 2009-2024
项目资助者: Fund of Capital Medical Development and Research
WOS记录号: WOS:000282547000001
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/61003
Appears in Collections:北京大学第三临床医学院_肿瘤放疗科_期刊论文

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作者单位: 1.Peking Univ, Hosp 3, Dept Radiat Oncol, Beijing 100191, Peoples R China
2.Peking Univ, Hosp 3, Dept Radiol, Beijing 100191, Peoples R China

Recommended Citation:
Jiang, Yu L.,Meng, Na,Wang, Jun J.,et al. CT-guided iodine-125 seed permanent implantation for recurrent head and neck cancers[J]. RADIATION ONCOLOGY,2010,5.
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