IR@PKUHSC  > 北京大学第三临床医学院  > 肿瘤放疗科
学科主题临床医学
CT-guided iodine-125 seed permanent implantation for recurrent head and neck cancers
Jiang, Yu L.1; Meng, Na1; Wang, Jun J.1; Jiang, Ping1; Yuan, Hui Sh2; Liu, Chen2; Qu, Ang1; Yang, Rui J.1
刊名RADIATION ONCOLOGY
2010-07-30
DOI10.1186/1748-717X-5-68
5
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Oncology ; Radiology, Nuclear Medicine & Medical Imaging
资助者Fund of Capital Medical Development and Research ; Fund of Capital Medical Development and Research
研究领域[WOS]Oncology ; Radiology, Nuclear Medicine & Medical Imaging
关键词[WOS]SQUAMOUS-CELL CANCER ; LIVER MALIGNANCIES ; RADIATION-THERAPY ; CAROTID-ARTERY ; I125 IMPLANTS ; BRACHYTHERAPY ; REIRRADIATION ; CARCINOMA ; TUMORS ; TONGUE
英文摘要

Background: To investigate the feasibility, and safety of (125)I seed permanent implantation for recurrent head and neck carcinoma under CT-guidance.

Results: A retrospective study on 14 patients with recurrent head and neck cancers undergone (125)I seed implantation with different seed activities. The post-plan showed that the actuarial D90 of (125)I seeds ranged from 90 to 218 Gy (median, 157.5 Gy). The follow-up was 3 to 60 months (median, 13 months). The median local control was 18 months (95% CI, 6.1-29.9 months), and the 1-, 2-, 3-, and 5-year local controls were 52%, 39%, 39%, and 39%, respectively. The 1-, 2-, 3-, and 5-survival rates were 65%, 39%, 39% and 39%, respectively, with a median survival time of 20 months (95% CI, 8.7-31.3 months). Of all patients, 28.6% (4/14) died of local recurrence, 7.1% (1/14) died of metastases, one patient died of hepatocirrhosis, and 8 patients are still alive to the date of data analysis.

Conclusion: CT-guided (125)I seed implantation is feasible and safe as a salvage or palliative treatment for patients with recurrent head and neck cancers.

语种英语
所属项目编号2009-2024
资助者Fund of Capital Medical Development and Research ; Fund of Capital Medical Development and Research
WOS记录号WOS:000282547000001
Citation statistics
Cited Times:28[WOS]   [WOS Record]     [Related Records in WOS]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/61003
Collection北京大学第三临床医学院_肿瘤放疗科
作者单位1.Peking Univ, Hosp 3, Dept Radiat Oncol, Beijing 100191, Peoples R China
2.Peking Univ, Hosp 3, Dept Radiol, Beijing 100191, Peoples R China
Recommended Citation
GB/T 7714
Jiang, Yu L.,Meng, Na,Wang, Jun J.,et al. CT-guided iodine-125 seed permanent implantation for recurrent head and neck cancers[J]. RADIATION ONCOLOGY,2010,5.
APA Jiang, Yu L..,Meng, Na.,Wang, Jun J..,Jiang, Ping.,Yuan, Hui Sh.,...&Yang, Rui J..(2010).CT-guided iodine-125 seed permanent implantation for recurrent head and neck cancers.RADIATION ONCOLOGY,5.
MLA Jiang, Yu L.,et al."CT-guided iodine-125 seed permanent implantation for recurrent head and neck cancers".RADIATION ONCOLOGY 5(2010).
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