|Natural history of benign prostate hyperplasia|
|Wu Shi-liang; Li Ning-chen; Xiao Yun-xiang; Jin Jie; Qiu Shao-peng; Ye Zhang-qun; Kong Chui-ze; Sun Guang; Na Yan-qun|
|关键词||benign prostate hyperplasia natural history epidemiology|
|刊名||CHINESE MEDICAL JOURNAL|
|WOS标题词||Science & Technology|
|类目[WOS]||Medicine, General & Internal|
|研究领域[WOS]||General & Internal Medicine|
|关键词[WOS]||URINARY-TRACT SYMPTOMS ; DIGITAL RECTAL EXAMINATION ; COMBINATION THERAPY ; FLOW-RATE ; CANCER ; MEN ; ANTIGEN ; AGE|
Background Benign prostate hyperplasia is one of the most common diseases affecting the health of the aging males. Watchful waiting is an acceptable management strategy for benign prostate hyperplasia in which the patient is monitored by the physician but receives no active intervention. The epidemiological data on this are lacking in China. Our study was designed to evaluate the changes of signs and symptoms of patients with benign prostate hyperplasia during management by watchful waiting in China.
Methods One hundred and forty-five patients with benign prostate hyperplasia aged > 50 years were enrolled in management by watchful waiting. All the patients were visited every 6 months and were given an International Prostate Symptom Score and Quality of Life questionnaire to complete. They also had uroflowmetry and were assessed using ultrasonography to get the volume of prostate, transition zone and amount of residual urine. The Student′s t test, the Chi-square test, and variance analysis were used in the statistical analysis.
Results All patients were visited after 6 months, the mean volume of transitional zone was found to have increased by 1.6 ml (P < 0.01), International Prostate Symptom Score was increased by 0.8 (P < 0.01) and Quality of Life was increased by 0.2 (P < 0.01), and there was no statistical change in other data. Among these patients, 17.9% (26/145) visited again after 12 months when the data failed to show a statistically significant difference among the three groups (0, 6, and 12 months).
Conclusions After one year′s follow-up, the progression of benign prostate hyperplasia was slow and the clinical data did not undergo much change.
|作者单位||1.Peking Univ, Hosp 1, Dept Urol, Beijing 100034, Peoples R China|
2.Zhongshan Univ, Affiliate Hosp 1, Dept Urol, Guangzhou 510080, Peoples R China
3.Huazhong Univ Sci & Technol, Tongji Med Coll, Tongji Hosp, Dept Urol, Wuhan 430030, Peoples R China
4.China Med Univ, Clin Hosp 1, Dept Urol, Shenyang 110001, Peoples R China
5.Tianjin Med Univ, Inst Urol, Tianjin 300211, Peoples R China
|Wu Shi-liang,Li Ning-chen,Xiao Yun-xiang,et al. Natural history of benign prostate hyperplasia[J]. CHINESE MEDICAL JOURNAL,2006,119(24):2085-2089.|
|APA||Wu Shi-liang.,Li Ning-chen.,Xiao Yun-xiang.,Jin Jie.,Qiu Shao-peng.,...&Na Yan-qun.(2006).Natural history of benign prostate hyperplasia.CHINESE MEDICAL JOURNAL,119(24),2085-2089.|
|MLA||Wu Shi-liang,et al."Natural history of benign prostate hyperplasia".CHINESE MEDICAL JOURNAL 119.24(2006):2085-2089.|