IR@PKUHSC  > 北京大学药学院
学科主题药学
A fructan, from radix ophiopogonis, stimulates the proliferation of cultured lymphocytes: Structural and functional analyses
Wu, Xiangmei; Dai, Hui; Huang, Lixin; Gao, Xiaoming; Tsim, Karl W. K.; Tu, Pengfei
刊名JOURNAL OF NATURAL PRODUCTS
2006-09-22
DOI10.1021/np060033d
69期:9页:1257-1260
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
研究领域[WOS]Plant Sciences ; Pharmacology & Pharmacy
关键词[WOS]ATOMIC-FORCE MICROSCOPY ; SUCROSE ; POLYSACCHARIDE ; POLYFRUCTAN ; METHYLATION ; SPECTRA ; CONIDIA ; INULIN ; ROOTS ; LEVAN
英文摘要

A fructan, Opaw-2, with molecular mass of about 14 kDa, was isolated from the tuberous roots of Ophiopogon japonicus. Opaw-2 comprises fructose and glucose with a molar ratio of 30: 1. Linkage and NMR analyses indicated that Opaw-2 has a backbone structure of beta-(1-->2)-Fruf and beta-(2-->6)-Fruf residues that branches at O-6 of beta-(1-->2)-Fruf residues with alpha-1-linkage to the Glcp residues and terminates with Fruf residues. In cultured lymphocytes, the application of Opaw-2 significantly stimulated the proliferation of lymphocytes in a dose-dependent manner. By using atomic force microscopy, Opaw-2 showed a morphological change from globular to helical fibrous shape at increasing concentrations.

语种英语
WOS记录号WOS:000240677700001
引用统计
被引频次:18[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/61024
专题北京大学药学院
作者单位1.Peking Univ, Hlth Sci Ctr, Sch Pharmaceut Sci, Modern Res Ctr Tradit Chinese Med, Beijing 100871, Peoples R China
2.Peking Univ, Hlth Sci Ctr, Sch Med Sci, Beijing 100871, Peoples R China
3.Hong Kong Univ Sci & Technol, Dept Biol, Hong Kong, Hong Kong, Peoples R China
推荐引用方式
GB/T 7714
Wu, Xiangmei,Dai, Hui,Huang, Lixin,et al. A fructan, from radix ophiopogonis, stimulates the proliferation of cultured lymphocytes: Structural and functional analyses[J]. JOURNAL OF NATURAL PRODUCTS,2006,69(9):1257-1260.
APA Wu, Xiangmei,Dai, Hui,Huang, Lixin,Gao, Xiaoming,Tsim, Karl W. K.,&Tu, Pengfei.(2006).A fructan, from radix ophiopogonis, stimulates the proliferation of cultured lymphocytes: Structural and functional analyses.JOURNAL OF NATURAL PRODUCTS,69(9),1257-1260.
MLA Wu, Xiangmei,et al."A fructan, from radix ophiopogonis, stimulates the proliferation of cultured lymphocytes: Structural and functional analyses".JOURNAL OF NATURAL PRODUCTS 69.9(2006):1257-1260.
条目包含的文件
条目无相关文件。
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Wu, Xiangmei]的文章
[Dai, Hui]的文章
[Huang, Lixin]的文章
百度学术
百度学术中相似的文章
[Wu, Xiangmei]的文章
[Dai, Hui]的文章
[Huang, Lixin]的文章
必应学术
必应学术中相似的文章
[Wu, Xiangmei]的文章
[Dai, Hui]的文章
[Huang, Lixin]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。