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Clinical and sociodemographic correlates of suicidality in patients with major depressive disorder from six Asian countries
Lim, Ah-Young1; Lee, Ah-Rong1; Hatim, Ahmad2; Tian-Mei, Si3; Liu, Chia-Yih4,5; Jeon, Hong Jin6; Udomratn, Pichet7; Bautista, Dianne8,9; Chan, Edwin8,9; Liu, Shen-Ing10; Chua, Hong Choon11; Hong, Jin Pyo1; MD RAN
关键词Suicide Major depressive disorder Risk factor Social support
刊名BMC PSYCHIATRY
2014-02-13
DOI10.1186/1471-244X-14-37
14
收录类别SCI ; SSCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Psychiatry
资助者H.Lundbeck A/S ; Duke-National University of Singapore Office of Clinical Research ; Korean Health Technology R&amp ; D Project, Ministry of Health &amp ; Welfare, Republic of Korea ; H.Lundbeck A/S ; Duke-National University of Singapore Office of Clinical Research ; Korean Health Technology R&amp ; D Project, Ministry of Health &amp ; Welfare, Republic of Korea
研究领域[WOS]Psychiatry
关键词[WOS]RISK-FACTORS ; DSM-IV ; SCALE ; CHINA ; GENDER ; SEVERITY ; UNIPOLAR ; BEHAVIOR ; IDEATION ; MINI
英文摘要

Background: East Asian countries have high suicide rates. However, little is known about clinical and sociodemographic factors associated with suicidality in Asian populations. The aim of this study was to evaluate the factors associated with suicidality in patients with major depressive disorder (MDD) from six Asian countries.

Methods: The study cohort consisted of 547 outpatients with MDD. Patients presented to study sites in China (n = 114), South Korea (n = 101), Malaysia (n = 90), Singapore (n = 40), Thailand (n = 103), and Taiwan (n = 99). All patients completed the Mini-International Neuropsychiatric Interview (MINI), the Montgomery-Asberg Depression Rating Scale (MADRS), the Global Severity Index(SCL-90R), the Fatigue Severity Scale, the 36-item short-form health survey, the Sheehan Disability Scale, and the Multidimensional Scale of Perceived Social Support (MSPSS). Patients were classified as showing high suicidality if they scored >= 6 on the MINI suicidality module. Multivariate logistic regression analysis was used to examine sociodemographic and clinical factors related to high suicidality.

Results: One hundred and twenty-five patients were classed as high suicidality. Unemployed status (adjusted odds ratio [OR] 2.43, p < 0.01), MADRS score (adjusted OR 1.08), p < 0.001, and GSI (SCL-90R) score (adjusted OR 1.06, p < 0.01) were positively related to high suicidality. Hindu (adjusted OR 0.09, p < 0.05) or Muslim (adjusted OR 0.21, p < 0.001) religion and MSPSS score (adjusted OR 0.82, p < 0.05) were protective against high suicidality.

Conclusions: A variety of sociodemographic and clinical factors were associated with high suicidality in Asian patients with MDD. These factors may facilitate the identification of MDD patients at risk of suicide.

语种英语
所属项目编号A120051
资助者H.Lundbeck A/S ; Duke-National University of Singapore Office of Clinical Research ; Korean Health Technology R&amp ; D Project, Ministry of Health &amp ; Welfare, Republic of Korea ; H.Lundbeck A/S ; Duke-National University of Singapore Office of Clinical Research ; Korean Health Technology R&amp ; D Project, Ministry of Health &amp ; Welfare, Republic of Korea
WOS记录号WOS:000332674500001
引用统计
被引频次:9[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/61026
专题北京大学精神卫生研究所
作者单位1.Chang Gung Univ, Tao Yuan, Taiwan
2.Singapore Clin Res Inst, Singapore, Singapore
3.Duke Natl Univ Singapore, Singapore, Singapore
4.Mackay Mem Hosp, Dept Psychiat, New Taipei City, Taiwan
5.Woodbridge Hosp, Inst Mental Hlth, Singapore, Singapore
6.Univ Malaya, Fac Med, Dept Psychol Med, Kuala Lumpur, Malaysia
7.Peking Univ, Inst Mental Hlth, Beijing 100871, Peoples R China
8.Chang Gung Med Ctr, Dept Psychiat, Tao Yuan, Taiwan
9.Univ Ulsan, Coll Med, Asan Med Ctr, Dept Psychiat, Seoul, South Korea
10.Sungkyunkwan Univ, Sch Med, Samsung Med Ctr, Depress Ctr,Dept Psychiat, Seoul, South Korea
11.Prince Songkla Univ, Fac Med, Dept Psychiat, Hat Yai, Thailand
推荐引用方式
GB/T 7714
Lim, Ah-Young,Lee, Ah-Rong,Hatim, Ahmad,et al. Clinical and sociodemographic correlates of suicidality in patients with major depressive disorder from six Asian countries[J]. BMC PSYCHIATRY,2014,14.
APA Lim, Ah-Young.,Lee, Ah-Rong.,Hatim, Ahmad.,Tian-Mei, Si.,Liu, Chia-Yih.,...&MD RAN.(2014).Clinical and sociodemographic correlates of suicidality in patients with major depressive disorder from six Asian countries.BMC PSYCHIATRY,14.
MLA Lim, Ah-Young,et al."Clinical and sociodemographic correlates of suicidality in patients with major depressive disorder from six Asian countries".BMC PSYCHIATRY 14(2014).
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