北京大学医学部机构知识库
Advanced  
IR@PKUHSC  > 北京大学第二临床医学院  > 放射科  > 期刊论文
学科主题: 临床医学
题名:
Diffusion-weighted MR imaging for assessing synovitis of wrist and hand in patients with rheumatoid arthritis: A feasibility study
作者: Li, Xubin1,2; Liu, Xia3; Du, Xiangke3; Ye, Zhaoxiang1,2
关键词: Rheumatoid arthritis ; Magnetic resonance imaging ; Diffusion-weighted imaging
刊名: MAGNETIC RESONANCE IMAGING
发表日期: 2014-05-01
DOI: 10.1016/j.mri.2013.12.008
卷: 32, 期:4, 页:350-353
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Radiology, Nuclear Medicine & Medical Imaging
研究领域[WOS]: Radiology, Nuclear Medicine & Medical Imaging
关键词[WOS]: FOLLOW-UP ; MANAGEMENT ; THERAPY ; DISEASE ; JOINT ; RA
英文摘要:

The purpose of this study was to investigate the feasibility of diffusion-weighted imaging (DWI) in detecting synovitis of wrist and hand in patients with rheumatoid arthritis (RA) and evaluate its sensitivity, specificity and accuracy as compared to T-2-weighted imaging (T2WI) with short tau inversion recovery (STIR) with the reference standard contrast-enhanced magnetic resonance imaging (CE-MRI). Twenty-five patients with RA underwent MR examinations including DWI, T2WI with STIR and CE-MRI. MR images were reviewed for the presence and location of synovitis of wrist and hand. The sensitivity, specificity and accuracy of DWI and T2WI with STIR were calculated respectively and then compared. All patients included in this study completed MR examinations and yielded diagnostic image quality of DWI. For individual joint, there was good to excellent inter-observer agreement (k = 0.62-0.83) using DWI images, T2WI with STIR images and CE-MR images, respectively. There was a significance between DWI and T2WI with STIR in analyzing proximal interphalangeal joints II-V, respectively (P < 0.05). The k-values for the detection of synovitis indicated excellent overall inter-observer agreements using DWI images (k = 0.86), T2WI with STIR images (k = 0.85) and CE-MR images (k = 0.91), respectively. Overall, DWI demonstrated a sensitivity, specificity and accuracy of 75.6%, 89.3% and 84.6%, respectively, for detection of synovitis, while 43.0%, 95.7% and 77.6% for T2WI with STIR, respectively. DWI showed positive lesions much better and more than T2WI with STIR. Our results indicate that DWI presents a novel non-invasive approach to contrast-free imaging of synovitis. It may play a role as an addition to standard protocols. (C) 2014 Elsevier Inc. All rights reserved.

语种: 英语
WOS记录号: WOS:000333868200006
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/61061
Appears in Collections:北京大学第二临床医学院_放射科_期刊论文

Files in This Item:

There are no files associated with this item.


作者单位: 1.Key Lab Canc Prevent & Therapy, Tianjin 300060, Peoples R China
2.Tianjin Med Univ Canc Inst & Hosp, Natl Clin Res Ctr Canc, Dept Radiol, Tianjin 300060, Peoples R China
3.Peking Univ, Peoples Hosp, Dept Radiol, Beijing 100044, Peoples R China

Recommended Citation:
Li, Xubin,Liu, Xia,Du, Xiangke,et al. Diffusion-weighted MR imaging for assessing synovitis of wrist and hand in patients with rheumatoid arthritis: A feasibility study[J]. MAGNETIC RESONANCE IMAGING,2014,32(4):350-353.
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[Li, Xubin]'s Articles
[Liu, Xia]'s Articles
[Du, Xiangke]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[Li, Xubin]‘s Articles
[Liu, Xia]‘s Articles
[Du, Xiangke]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit
所有评论 (0)
暂无评论
 
评注功能仅针对注册用户开放,请您登录
您对该条目有什么异议,请填写以下表单,管理员会尽快联系您。
内 容:
Email:  *
单位:
验证码:   刷新
您在IR的使用过程中有什么好的想法或者建议可以反馈给我们。
标 题:
 *
内 容:
Email:  *
验证码:   刷新

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Copyright © 2007-2017  北京大学医学部 - Feedback
Powered by CSpace