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Diffusion-weighted MR imaging for assessing synovitis of wrist and hand in patients with rheumatoid arthritis: A feasibility study
Li, Xubin1,2; Liu, Xia3; Du, Xiangke3; Ye, Zhaoxiang1,2
关键词Rheumatoid arthritis Magnetic resonance imaging Diffusion-weighted imaging
刊名MAGNETIC RESONANCE IMAGING
2014-05-01
DOI10.1016/j.mri.2013.12.008
32期:4页:350-353
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Radiology, Nuclear Medicine & Medical Imaging
研究领域[WOS]Radiology, Nuclear Medicine & Medical Imaging
关键词[WOS]FOLLOW-UP ; MANAGEMENT ; THERAPY ; DISEASE ; JOINT ; RA
英文摘要

The purpose of this study was to investigate the feasibility of diffusion-weighted imaging (DWI) in detecting synovitis of wrist and hand in patients with rheumatoid arthritis (RA) and evaluate its sensitivity, specificity and accuracy as compared to T-2-weighted imaging (T2WI) with short tau inversion recovery (STIR) with the reference standard contrast-enhanced magnetic resonance imaging (CE-MRI). Twenty-five patients with RA underwent MR examinations including DWI, T2WI with STIR and CE-MRI. MR images were reviewed for the presence and location of synovitis of wrist and hand. The sensitivity, specificity and accuracy of DWI and T2WI with STIR were calculated respectively and then compared. All patients included in this study completed MR examinations and yielded diagnostic image quality of DWI. For individual joint, there was good to excellent inter-observer agreement (k = 0.62-0.83) using DWI images, T2WI with STIR images and CE-MR images, respectively. There was a significance between DWI and T2WI with STIR in analyzing proximal interphalangeal joints II-V, respectively (P < 0.05). The k-values for the detection of synovitis indicated excellent overall inter-observer agreements using DWI images (k = 0.86), T2WI with STIR images (k = 0.85) and CE-MR images (k = 0.91), respectively. Overall, DWI demonstrated a sensitivity, specificity and accuracy of 75.6%, 89.3% and 84.6%, respectively, for detection of synovitis, while 43.0%, 95.7% and 77.6% for T2WI with STIR, respectively. DWI showed positive lesions much better and more than T2WI with STIR. Our results indicate that DWI presents a novel non-invasive approach to contrast-free imaging of synovitis. It may play a role as an addition to standard protocols. (C) 2014 Elsevier Inc. All rights reserved.

语种英语
WOS记录号WOS:000333868200006
引用统计
被引频次:13[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/61061
专题北京大学第二临床医学院_放射科
作者单位1.Key Lab Canc Prevent & Therapy, Tianjin 300060, Peoples R China
2.Tianjin Med Univ Canc Inst & Hosp, Natl Clin Res Ctr Canc, Dept Radiol, Tianjin 300060, Peoples R China
3.Peking Univ, Peoples Hosp, Dept Radiol, Beijing 100044, Peoples R China
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GB/T 7714
Li, Xubin,Liu, Xia,Du, Xiangke,et al. Diffusion-weighted MR imaging for assessing synovitis of wrist and hand in patients with rheumatoid arthritis: A feasibility study[J]. MAGNETIC RESONANCE IMAGING,2014,32(4):350-353.
APA Li, Xubin,Liu, Xia,Du, Xiangke,&Ye, Zhaoxiang.(2014).Diffusion-weighted MR imaging for assessing synovitis of wrist and hand in patients with rheumatoid arthritis: A feasibility study.MAGNETIC RESONANCE IMAGING,32(4),350-353.
MLA Li, Xubin,et al."Diffusion-weighted MR imaging for assessing synovitis of wrist and hand in patients with rheumatoid arthritis: A feasibility study".MAGNETIC RESONANCE IMAGING 32.4(2014):350-353.
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