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IR@PKUHSC  > 北京大学药学院  > 化学生物学系  > 期刊论文
学科主题: 药学
题名:
Effects of lanthanide ions on hydrolysis of phosphatidylinositol in human erythrocyte membranes
作者: Liu, HX; Hu, J; Liu, XT; Li, RC; Wang, K
关键词: lanthanids ions ; phosphatidylinositol ; second messengers
刊名: CHINESE SCIENCE BULLETIN
发表日期: 2001-03-01
卷: 46, 期:5, 页:401-403
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Multidisciplinary Sciences
研究领域[WOS]: Science & Technology - Other Topics
英文摘要:

The effects of lanthanides on the hydrolysis of phosphatidylinositol in human erythrocyte membranes were studied. H-3-inositol labeling chromatography and HPLC were used to determine inositol 1, 4, 5-triphosphate and diacylglycerol separately, the hydrolytic products of phosphatidylinositol due to the reaction of lanthanide ions with human erythrocyte membranes. The unhydrolyzed phosphatidylinositol in membranes was also determined. The results indicate that the hydrolysis of phosphatidylinositol can be promoted by lanthanides (La3+, Ce3+, Y3+, Tb3+) and the effects of La3+ and Ce3+ are stronger than those of Y3+ and Tb3+.

语种: 英语
WOS记录号: WOS:000168244600013
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/61202
Appears in Collections:北京大学药学院_化学生物学系_期刊论文

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作者单位: Beijing Med Univ, Sch Pharmaceut Sci, Dept Biol Chem, Beijing 100083, Peoples R China

Recommended Citation:
Liu, HX,Hu, J,Liu, XT,et al. Effects of lanthanide ions on hydrolysis of phosphatidylinositol in human erythrocyte membranes[J]. CHINESE SCIENCE BULLETIN,2001,46(5):401-403.
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