IR@PKUHSC  > 中国药物依赖性研究所
学科主题药物依赖
Opiate addiction in China: current situation and treatments
Tang, YL; Zhao, D; Zhao, CZ; Cubells, JF
关键词China detoxification drug addiction epidemiology methadone maintenance opiate
刊名ADDICTION
2006-05-01
DOI10.1111/j.1360-0443.2006.01367.x
101期:5页:657-665
收录类别SCI ; SSCI
文章类型Review
WOS标题词Science & Technology
类目[WOS]Substance Abuse ; Psychiatry
研究领域[WOS]Substance Abuse ; Psychiatry
关键词[WOS]HIGH-PREVALENCE AREAS ; USE PATTERNS ; DRUG-USE ; WITHDRAWAL SYMPTOMS ; OPIOID DEPENDENCE ; HEROIN-ADDICTION ; CONTROLLED TRIAL ; METHADONE ; DETOXIFICATION ; BUPRENORPHINE
英文摘要

Background Historically, China has had extraordinarily high rates of opiate dependence. These rates declined drastically following the 1949 revolution; however, opiate abuse has re-emerged in the late 1980′s and has spread quickly since then. Aims To describe the current situation of opiate addiction and treatments in China and make some suggestions. Design A descriptive study based on literature searched from Medline and the China National Knowledge Infrastructure database (1996 to 2004) and hand-picked references. Findings The number of registered addicts in 2004 was 1.14 million (more than 75% of them heroin addicts), but the actual number is probably far higher. Opiate abuse contributes substantially to the spread of HIV/AIDS in China, with intravenous drug use the most prevalent route of transmission (51.2%). Currently, the main treatments for opiate dependence in China include short-term detoxification with opiate agonists or non-opiate agents, such as clonidine or lofexidine; Chinese herbal medicine and traditional non-medication treatments are also used. Methadone maintenance treatment (MMT) has not been officially approved by the Chinese government for widespread implementation, but some pilot studies are currently underway. Conclusion China faces substantial drug abuse problems that appear to be worsening with time. Opiate dependence is a major threat to the public health and social security of China because of its devastating medical effects, its impact on risk for HIV/AIDS and criminal behaviors, low rates of recovery and high rates of relapse. There is an urgent need to implement MMT and other modern treatments for opiate dependence more widely in China.

语种英语
WOS记录号WOS:000236911800021
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被引频次:91[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/61242
专题中国药物依赖性研究所
作者单位1.Emory Univ, Dept Human Genet, Sch Med, Atlanta, GA 30322 USA
2.Emory Univ, Dept Psychiat & Behav Sci, Sch Med, Atlanta, GA 30322 USA
3.Capital Univ Med Sci, Beijing Anding Hosp, Beijing, Peoples R China
4.Peking Univ, Natl Inst Drug Dependence, Beijing 100871, Peoples R China
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GB/T 7714
Tang, YL,Zhao, D,Zhao, CZ,et al. Opiate addiction in China: current situation and treatments[J]. ADDICTION,2006,101(5):657-665.
APA Tang, YL,Zhao, D,Zhao, CZ,&Cubells, JF.(2006).Opiate addiction in China: current situation and treatments.ADDICTION,101(5),657-665.
MLA Tang, YL,et al."Opiate addiction in China: current situation and treatments".ADDICTION 101.5(2006):657-665.
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