IR@PKUHSC  > 北京大学基础医学院  > 病原生物学系
学科主题基础医学
Relative Low Glycometabolism May Also Occur in Invasive Lung Adenocarcinoma With Visceral Pleural Invasion: Case Report and Comments
Jiang, Chunyang1; Han, Youkui1; Hu, Xiaoli2; Yang, Bingjun1; Tang, Tao3; Chen, Xiangmei4,5; Zhao, Hui1
刊名MEDICINE
2014-12-01
DOI10.1097/MD.0000000000000254
93期:26
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Medicine, General & Internal
资助者National Natural Science Foundation of China ; National Natural Science Foundation of China
研究领域[WOS]General & Internal Medicine
关键词[WOS]CANCER ; THERAPY
英文摘要

Lung cancer is the main cause of cancer deaths in the world and positron emission tomography (PET) is considered as the most accurate diagnosis and staging technique for lung cancer. For human cancers, fluorodeoxyglucose (FDG)-PET imaging of most primary and metastatic tumors will show significantly increased glucose uptake because high metabolic activity of cancer cells. But there still have the question of false negative or positive rates in diagnostic accuracy need to be considered.A 51 year old man was diagnosed a lung tumor in the right middle lobe without enlargement of lymph nodes by computed tomography (CT). The F-18-FDG-PET/CT presented 1 slight increased metabolism in the tumor region. After resection of the tumor, postoperative pathological examination confirmed that it was invasive lung adenocarcinoma and with visceral pleural invasion while showed relative low glucose absorption in PET/CT.A form of invasive lung adenocarcinoma was diagnosized. The tumor tissues were further confirmed by immunohistochemical assessments, which showed that thyroid transcription factor 1 (TTF-1 or NKX2-1) and Cytokeratin 7 (CK7) were all significant positive.Diagnosis of lung cancer even all other cancers by FDG-PET should be carefully considered the question of accuracy. Our case has added additional literature for us to considering the false-negative of lung cancer diagnosis by F-18-FDG-PET/CT.

语种英语
所属项目编号81101539 ; 81372603
资助者National Natural Science Foundation of China ; National Natural Science Foundation of China
WOS记录号WOS:000346257000014
Citation statistics
文献类型期刊论文
版本出版稿
条目标识符http://ir.bjmu.edu.cn/handle/400002259/61307
Collection北京大学基础医学院_病原生物学系
作者单位1.Tianjin Union Med Ctr, Dept Thorac Surg, Tianjin 300121, Peoples R China
2.Peoples Hosp Qitaihe City, Dept Resp Med, Qitaihe 154600, Heilongjiang, Peoples R China
3.Tianjin Union Med Ctr, Dept Pathol, Tianjin 300121, Peoples R China
4.Peking Univ, Hlth Sci Ctr, Sch Basic Med Sci, Dept Microbiol, Beijing 100191, Peoples R China
5.Peking Univ, Hlth Sci Ctr, Sch Basic Med Sci, Ctr Infect Dis, Beijing 100191, Peoples R China
Recommended Citation
GB/T 7714
Jiang, Chunyang,Han, Youkui,Hu, Xiaoli,et al. Relative Low Glycometabolism May Also Occur in Invasive Lung Adenocarcinoma With Visceral Pleural Invasion: Case Report and Comments[J]. MEDICINE,2014,93(26).
APA Jiang, Chunyang.,Han, Youkui.,Hu, Xiaoli.,Yang, Bingjun.,Tang, Tao.,...&Zhao, Hui.(2014).Relative Low Glycometabolism May Also Occur in Invasive Lung Adenocarcinoma With Visceral Pleural Invasion: Case Report and Comments.MEDICINE,93(26).
MLA Jiang, Chunyang,et al."Relative Low Glycometabolism May Also Occur in Invasive Lung Adenocarcinoma With Visceral Pleural Invasion: Case Report and Comments".MEDICINE 93.26(2014).
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