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学科主题: 公共卫生
题名:
Relationship between Ambient Fine Particles and Ventricular Repolarization Changes and Heart Rate Variability of Elderly People with Heart Disease in Beijing, China
作者: Xu Mei Mei1; Jia Yu Ping2; Li Guo Xing1; Liu Li Qun3; Mo Yun Zheng1; Jin Xiao Bin1; Pan Xiao Chuan1
关键词: PM2.5 ; Repolarization ; Heart rate variability ; Elderly ; Panel study
刊名: BIOMEDICAL AND ENVIRONMENTAL SCIENCES
发表日期: 2013-08-01
DOI: 10.3967/0895-3988.2013.08.001
卷: 26, 期:8, 页:629-637
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Environmental Sciences ; Public, Environmental & Occupational Health
研究领域[WOS]: Environmental Sciences & Ecology ; Public, Environmental & Occupational Health
关键词[WOS]: PARTICULATE AIR-POLLUTION ; CORONARY-ARTERY-DISEASE ; CARDIAC AUTONOMIC CONTROL ; SHORT-TERM EXPOSURE ; PROGNOSTIC VALUE ; MORTALITY ; ASSOCIATION ; POPULATION ; FAILURE ; MATTER
英文摘要:

Objective To explore the effects of particulate matters less than 2.5 mu m in aerodynamic diameter (PM2.5) on heart repolarization/depolarization and heart rate variability (HRV).

Methods We conducted a panel study for elderly subjects with heart disease in Beijing from 2007 to 2008. PM2.5 was measured at a fixed station for 20 h continuously each day while electrocardiogram (ECG) indexes of 42 subjects were also recorded repeatedly. Meteorological data was obtained from the China Meteorological Data Sharing Service System. A mixed linear regression model was used to estimate the associations between PM2.5 and the ECG indexes. The model was adjusted for age, body mass index, sex, day of the week and meteorology.

Results Significant adverse effects of PM2.5 on ECG indexes reflecting HRV were observed statistically and the strongest effect of PM2.5 on HRV was on lag 1 day in our study. However, there were no associations between PM2.5 and ECG indexes reflecting heart repolarization/depolarization. Additionally, the effects of PM2.5 on subjects with hypertension were larger than on the subjects without hypertension.

Conclusion This study showed ambient PM2.5 could affect cardiac autonomic function of the elderly people with heart disease, and subjects with hypertension appeared to be more susceptive to the autonomic dysfunction induced by PM2.5.

语种: 英语
所属项目编号: 20637020
项目资助者: National Natural Science Foundation of China
WOS记录号: WOS:000324294900001
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/61432
Appears in Collections:北京大学公共卫生学院_期刊论文

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作者单位: 1.German Res Ctr Environm Hlth, Inst Epidemiol, D-85764 Munich, Germany
2.Peking Univ, Dept Occupat & Environm Hlth, Sch Publ Hlth, Beijing 100191, Peoples R China
3.Beijing Ctr Dis Control & Prevent, Inst Environm Hlth, Beijing 100013, Peoples R China

Recommended Citation:
Xu Mei Mei,Jia Yu Ping,Li Guo Xing,et al. Relationship between Ambient Fine Particles and Ventricular Repolarization Changes and Heart Rate Variability of Elderly People with Heart Disease in Beijing, China[J]. BIOMEDICAL AND ENVIRONMENTAL SCIENCES,2013,26(8):629-637.
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