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Salivary duct carcinoma of the parotid gland: A case report and review of the literature
Xie, Shule1,2; Yang, Hongyu1; Bredell, Marius3; Shen, Shiyue1; Yang, Huijun1; Jin, Long1; Zhang, Shanshan1,2
关键词salivary duct carcinoma salivary gland clinic immunohistology
刊名ONCOLOGY LETTERS
2015
DOI10.3892/ol.2014.2655
9期:1页:371-374
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Oncology
研究领域[WOS]Oncology
关键词[WOS]EXPRESSION ; TUMORS
英文摘要

Salivary duct carcinoma (SDC) is a rare and aggressive parotid malignancy that most commonly affects males in the fifth and sixth decades of life. Histopathology specimens obtained from SDC patients demonstrate a resemblance to ductal carcinoma of the breast. Therefore, to distinguish SDC from breast ductal carcinoma, several immunohistochemical markers exist that may enable surgeons to make an accurate diagnosis. In this study, the case of a 54-year-old male with salivary duct carcinoma of the right parotid gland is presented. The results of the present case study revealed that the SDC sample was positive for the expression of human epidermal growth factor 2 (Her-2), cytokeratin (CK) 8/CK 18, p63, high molecular weight CK and calponin, and negative for expression of the estrogen receptor and progesterone receptor. Based on the result, an ipsilateral selective neck dissection followed by adjuvant post-operative radiation therapy was suitable at the primary treatment stage. At one year of follow-up, the patient was alive and free of recurrence. In advanced cases of SDC, treatment with anti-HER-2 monoclonal antibodies, such as trastuzumab, is recommended.

语种英语
WOS记录号WOS:000346638300070
引用统计
被引频次:2[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/61435
专题北京大学深圳医院
北京大学第三临床医学院_眼科
北京大学口腔医学院_口腔预防保健科
作者单位1.Peking Univ, Shenzhen Hosp, Dept Oral & Maxillofacial Surg, Shenzhen 518001, Guangdong, Peoples R China
2.Shantou Univ, Coll Med, Shantou 515041, Guangdong, Peoples R China
3.Univ Zurich Hosp, Dept Craniomaxillofacial & Oral Surg, CH-8091 Zurich, Switzerland
推荐引用方式
GB/T 7714
Xie, Shule,Yang, Hongyu,Bredell, Marius,et al. Salivary duct carcinoma of the parotid gland: A case report and review of the literature[J]. ONCOLOGY LETTERS,2015,9(1):371-374.
APA Xie, Shule.,Yang, Hongyu.,Bredell, Marius.,Shen, Shiyue.,Yang, Huijun.,...&Zhang, Shanshan.(2015).Salivary duct carcinoma of the parotid gland: A case report and review of the literature.ONCOLOGY LETTERS,9(1),371-374.
MLA Xie, Shule,et al."Salivary duct carcinoma of the parotid gland: A case report and review of the literature".ONCOLOGY LETTERS 9.1(2015):371-374.
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