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学科主题: 药学
题名:
Toward breast cancer resistance protein (BCRP) inhibitors: design, synthesis of a series of new simplified fumitremorgin C analogues
作者: Wu, Guofeng3; Liu, Jiawang3; Bi, Lanrong2; Zhao, Ming1,2; Wang, Chao3; Baudy-Floc′ h, Michele4; Ju, Jingfang1; Peng, Shiqi1,2
关键词: fumitremorgin C analogues ; breast cancer resistance protein inhibitors ; enantioselective synthesis ; racemization ; coupling
刊名: TETRAHEDRON
发表日期: 2007-06-18
DOI: 10.1016/j.tet.2007.04.045
卷: 63, 期:25, 页:5510-5528
收录类别: SCI ; IC
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Chemistry, Organic
研究领域[WOS]: Chemistry
关键词[WOS]: MULTIDRUG-RESISTANCE ; DRUG-RESISTANCE ; SOLID-PHASE ; EFFLUX TRANSPORTERS ; COUPLING REAGENTS ; PEPTIDE-SYNTHESIS ; P-GLYCOPROTEIN ; MECHANISM ; REVERSAL ; CELLS
英文摘要:

In this study, we report the design and synthesis of a series of new simplified fumitremorgin C analogues. The preliminary biological study indicated some of these simplified fumitremorgin C might be developed into breast cancer resistance inhibitors. (c) 2007 Elsevier Ltd. All rights reserved.

语种: 英语
WOS记录号: WOS:000252076300017
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/61454
Appears in Collections:北京大学药学院_期刊论文

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作者单位: 1.Univ S Alabama, Mitchell Canc Inst, Mobile, AL 36688 USA
2.Capital Med Univ, Coll Pharmaceut Sci, Beijing 100069, Peoples R China
3.Peking Univ, Coll Pharmaceut Sci, Beijing 100083, Peoples R China
4.Univ Rennes 1, Grp Ciblage & Autoassemblages Fonctionels, CNRS, UMR 6226, F-35042 Rennes, France

Recommended Citation:
Wu, Guofeng,Liu, Jiawang,Bi, Lanrong,et al. Toward breast cancer resistance protein (BCRP) inhibitors: design, synthesis of a series of new simplified fumitremorgin C analogues[J]. TETRAHEDRON,2007,63(25):5510-5528.
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