IR@PKUHSC  > 北京大学第二临床医学院  > 心外科
学科主题临床医学
Effects of Anxiety and Depression on Arterial Elasticity of Subjects With Suboptimal Physical Health
Sun, Ningling1; Xi, Yang1; Zhu, Zhiming2; Yin, Huijun3; Tao, Qiushan4; Wang, Hongyi1; Wang, Luyan1; Ma, Zhiyi1; Chen, Yuanyuan1; Yao, Dan1
刊名CLINICAL CARDIOLOGY
2015-10-01
DOI10.1002/clc.22455
38期:10页:614-620
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Cardiac & Cardiovascular Systems
研究领域[WOS]Cardiovascular System & Cardiology
关键词[WOS]CORONARY-HEART-DISEASE ; CARDIOVASCULAR-DISEASE ; OF-CARDIOLOGY ; RISK-FACTORS ; STIFFNESS ; STRESS ; VASODILATION ; HYPERTENSION ; ASSOCIATION ; DYSFUNCTION
英文摘要

BackgroundThe authors investigated the effects of suboptimal health status (SHS; high-normal blood pressure, blood glucose, and blood lipids) on arterial elasticity in subjects with or without anxiety or depression.

HypothesisSuboptimal physical health status and anxiety or depression increase the risk of cardiovascular diseases.

MethodsThis was a cross-sectional, observational, multicenter study. Among 1520 subjects who underwent physical examination between May 2009 and December 2012 in Beijing and Chongqing, China, 955 were included. All subjects completed anxiety and depression questionnaires. Systemic vascular compliance (SVC), systemic vascular resistance, and brachial artery distensibility (BAD) were measured during arterial elasticity evaluation.

ResultsOf 955 participants, 633 were classified as having SHS and 322 were classified as healthy. Systemic vascular compliance and BAD were worse in SHS subjects than in healthy subjects (SVC: 1.23 0.22 vs 1.29 +/- 0.25 mL/mm Hg; BAD: 6.26 +/- 1.32 vs 6.61 +/- 1.24%/mm Hg, respectively; both P < 0.05). Of 955 subjects, 37.7% and 43.9% had anxiety and depression, respectively. Systemic vascular compliance and BAD in SHS subjects with concomitant anxiety or depression were significantly lower than in SHS subjects without anxiety or depression (SVC: 1.22 +/- 0.23 vs 1.23 +/- 0.20 mL/mm Hg; BAD: 6.10 +/- 1.36 vs 6.33 +/- 1.20 %/mm Hg, respectively; both P < 0.05) and even lower than in healthy subjects.

ConclusionsThough anxiety and depression had less impact on arterial elasticity in a healthy population, they may be involved in pathogenesis of vascular damage in the population with SHS.

语种英语
WOS记录号WOS:000363666600006
引用统计
被引频次:1[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/61476
专题北京大学第二临床医学院_心外科
北京大学第二临床医学院_心血管内科
作者单位1.Peking Univ, Ctr Heart, Peoples Hosp, Beijing 100044, Peoples R China
2.Third Mil Med Univ, Hypertens & Metab Dis Ctr, Affiliated Hosp 3, Chongqing, Peoples R China
3.China Acad Tradit Chinese Med, Xiyuan Hosp, Dept Cardiol, Beijing, Peoples R China
4.Peking Univ, Dept Heart Ctr, Hypertens Lab, Sch Publ Hlth, Beijing 100044, Peoples R China
推荐引用方式
GB/T 7714
Sun, Ningling,Xi, Yang,Zhu, Zhiming,et al. Effects of Anxiety and Depression on Arterial Elasticity of Subjects With Suboptimal Physical Health[J]. CLINICAL CARDIOLOGY,2015,38(10):614-620.
APA Sun, Ningling.,Xi, Yang.,Zhu, Zhiming.,Yin, Huijun.,Tao, Qiushan.,...&Yao, Dan.(2015).Effects of Anxiety and Depression on Arterial Elasticity of Subjects With Suboptimal Physical Health.CLINICAL CARDIOLOGY,38(10),614-620.
MLA Sun, Ningling,et al."Effects of Anxiety and Depression on Arterial Elasticity of Subjects With Suboptimal Physical Health".CLINICAL CARDIOLOGY 38.10(2015):614-620.
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