北京大学医学部机构知识库
Advanced  
IR@PKUHSC  > 北京大学深圳医院  > 生殖医学科  > 期刊论文
学科主题: 临床医学
题名:
Variations in parametrial white adipose tissue mass during the mouse estrous cycle: relationship with the expression of peroxisome proliferator-activated receptor-gamma and retinoic acid receptor-alpha
作者: Gui, Yaoting; Cai, Zhiming; Silha, Josef V.; Murphy, Liam J.
关键词: adipose tissues ; estrous cycle ; mouse ; PPAR gamma ; RXR alpha
刊名: CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY
发表日期: 2006-08-01
DOI: 10.1139/Y06-032
卷: 84, 期:8-9, 页:887-892
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Pharmacology & Pharmacy ; Physiology
研究领域[WOS]: Pharmacology & Pharmacy ; Physiology
关键词[WOS]: INSULIN-RESISTANCE ; X-RECEPTOR ; CROSS-TALK ; MICE ; OBESITY ; GLUCOSE ; LEPTIN ; RATS
英文摘要:

Estrogen and progestin participate in the regulation of adipose tissue metabolism, and peroxisome proliferator-activated receptor-gamma (PPAR gamma) and retinoic acid receptor-alpha (RXR alpha) are absolutely required for adipose tissue development. The present study is to investigate the changes in parametrial fat mass and expression of PPAR gamma and RXR alpha during estrous cycle in mice. Parametrial white adipose tissues (WAT), inter-scapula brown adipose tissues, and uteri from female mice were weighed. Blood samples were collected for the measurement of 17 beta-estradiol and progesterone levels. An RNase protection assay and Western blot analysis were used to compare the expression of PPAR gamma and RXR alpha in adipose tissue. The mass of parametrial WAT in diestrus was significantly higher compared with estrus. However, there is no significant difference on the mass of brown adipose tissues during estrous cycle. The expression of PPAR gamma in WAT in diestrus was significantly higher than that in estrus. The expression of RXR alpha during estrous cycle was unchanged in both white and brown adipose tissues. In conclusion, the variation in parametrial WAT mass during the mouse estrous cycle correlates with changes in the expression of PPAR gamma in WAT.

语种: 英语
WOS记录号: WOS:000242210800009
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/61493
Appears in Collections:北京大学深圳医院_生殖医学科_期刊论文

Files in This Item:

There are no files associated with this item.


作者单位: 1.Univ Manitoba, Dept Physiol, Winnipeg, MB R3E 0W3, Canada
2.Peking Univ, Shenzhen Hosp, Ctr Reprod Med, Shenzhen 518036, Peoples R China

Recommended Citation:
Gui, Yaoting,Cai, Zhiming,Silha, Josef V.,et al. Variations in parametrial white adipose tissue mass during the mouse estrous cycle: relationship with the expression of peroxisome proliferator-activated receptor-gamma and retinoic acid receptor-alpha[J]. CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY,2006,84(8-9):887-892.
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[Gui, Yaoting]'s Articles
[Cai, Zhiming]'s Articles
[Silha, Josef V.]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[Gui, Yaoting]‘s Articles
[Cai, Zhiming]‘s Articles
[Silha, Josef V.]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Copyright © 2007-2017  北京大学医学部 - Feedback
Powered by CSpace