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学科主题: 药学
题名:
Two new phenolic glycosides from the barks of Hydnocarpus annamensis and their anti-inflammatory and anti-oxidation activities
作者: Shi, Hai-Ming; Wen, Jing; Jia, Cun-Qin; Jin, Wei; Zhang, Xiu-Feng; Yao, Zhi-Rong; Tu, Peng-Fei
刊名: PLANTA MEDICA
发表日期: 2006-08-01
DOI: 10.1055/s-2006-946678
卷: 72, 期:10, 页:948-950
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
研究领域[WOS]: Plant Sciences ; Pharmacology & Pharmacy
关键词[WOS]: CONSTITUENTS ; LEAVES ; PHENYLPROPANOIDS ; DERIVATIVES ; LIGNANS ; SERIES
英文摘要:

Two new phenolic glycosides 1 and 2 were isolated from the barks of Hydnocarpus annamensis, along with eighteen known compounds. The structures of all compounds were deduced using spectroscopic methods. Anti-inflammatory and anti-oxidation activities were evaluated. Among the isolates, compounds 1, 5,15 and 17 exhibited COX-2 inhibitory activities, with an inhibitory rate of 60.3-63.4% at 10 mu M. Compounds 7,12,13 and 20 showed anti-oxidation capacities in the DPPH free-radical assay, with a scavenging effect of 60.9-69.4% at 50 mu M, and 18.5-34.6% at 10 mu M.

语种: 英语
WOS记录号: WOS:000240478500018
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/61499
Appears in Collections:北京大学药学院_天然药物学系_期刊论文

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作者单位: 1.Peking Univ, Hlth Sci Ctr, Sch Pharmaceut Sci, Dept Nat Med, Beijing 100083, Peoples R China
2.Chinese Acad Sci, Inst Chem, Ctr Mol Sci, State Key Lab Struct Chem Unstable & Stable Speci, Beijing 100080, Peoples R China

Recommended Citation:
Shi, Hai-Ming,Wen, Jing,Jia, Cun-Qin,et al. Two new phenolic glycosides from the barks of Hydnocarpus annamensis and their anti-inflammatory and anti-oxidation activities[J]. PLANTA MEDICA,2006,72(10):948-950.
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