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Two new phenolic glycosides from the barks of Hydnocarpus annamensis and their anti-inflammatory and anti-oxidation activities
Shi, Hai-Ming; Wen, Jing; Jia, Cun-Qin; Jin, Wei; Zhang, Xiu-Feng; Yao, Zhi-Rong; Tu, Peng-Fei
刊名PLANTA MEDICA
2006-08-01
DOI10.1055/s-2006-946678
72期:10页:948-950
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
研究领域[WOS]Plant Sciences ; Pharmacology & Pharmacy
关键词[WOS]CONSTITUENTS ; LEAVES ; PHENYLPROPANOIDS ; DERIVATIVES ; LIGNANS ; SERIES
英文摘要

Two new phenolic glycosides 1 and 2 were isolated from the barks of Hydnocarpus annamensis, along with eighteen known compounds. The structures of all compounds were deduced using spectroscopic methods. Anti-inflammatory and anti-oxidation activities were evaluated. Among the isolates, compounds 1, 5,15 and 17 exhibited COX-2 inhibitory activities, with an inhibitory rate of 60.3-63.4% at 10 mu M. Compounds 7,12,13 and 20 showed anti-oxidation capacities in the DPPH free-radical assay, with a scavenging effect of 60.9-69.4% at 50 mu M, and 18.5-34.6% at 10 mu M.

语种英语
WOS记录号WOS:000240478500018
引用统计
被引频次:14[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/61499
专题北京大学药学院_天然药物学系
作者单位1.Peking Univ, Hlth Sci Ctr, Sch Pharmaceut Sci, Dept Nat Med, Beijing 100083, Peoples R China
2.Chinese Acad Sci, Inst Chem, Ctr Mol Sci, State Key Lab Struct Chem Unstable & Stable Speci, Beijing 100080, Peoples R China
推荐引用方式
GB/T 7714
Shi, Hai-Ming,Wen, Jing,Jia, Cun-Qin,et al. Two new phenolic glycosides from the barks of Hydnocarpus annamensis and their anti-inflammatory and anti-oxidation activities[J]. PLANTA MEDICA,2006,72(10):948-950.
APA Shi, Hai-Ming.,Wen, Jing.,Jia, Cun-Qin.,Jin, Wei.,Zhang, Xiu-Feng.,...&Tu, Peng-Fei.(2006).Two new phenolic glycosides from the barks of Hydnocarpus annamensis and their anti-inflammatory and anti-oxidation activities.PLANTA MEDICA,72(10),948-950.
MLA Shi, Hai-Ming,et al."Two new phenolic glycosides from the barks of Hydnocarpus annamensis and their anti-inflammatory and anti-oxidation activities".PLANTA MEDICA 72.10(2006):948-950.
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