北京大学医学部机构知识库
Advanced  
IR@PKUHSC  > 北京大学药学院  > 期刊论文
学科主题: 药学
题名:
Chemical fingerprint of commercial Radix Echinopsis and quantitative analysis of alpha-terthienyl
作者: Qiao, Xue; Han, Jian; He, Wen-ni; Wu, Tao; Wang, Bao-rong; Ye, Min; Guo, De-an
关键词: Chemical fingerprint ; LC/MS ; Quality control ; Radix Echinopsis ; Thiophenes
刊名: JOURNAL OF SEPARATION SCIENCE
发表日期: 2010-03-01
DOI: 10.1002/jssc.200900613
卷: 33, 期:4-5, 页:530-538
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Chemistry, Analytical
研究领域[WOS]: Chemistry
关键词[WOS]: RHAPONTICUM-UNIFLORUM ; THIOPHENES ; LATIFOLIUS ; GRIJISII
英文摘要:

New TLC, HPLC and LC/MS methods were developed for the rapid separation, characterization and quantitation of thiophenes in Radix Echinopsis, a herbal medicine, which has been used in China for long history. Nineteen commercial batches of this herb were analyzed by TLC and HPLC. Only five batches were derived from correct species. The other 14 batches were identified as its adulterating species, Radix Rhapontici, as they did not contain characteristic thiophenes of Echinopsis species. By LC/MS, 16 thiophenes were identified from the methanol extracts of Radix Echinopsis and Radix Rhapontici according to their fragmentation behaviors in MS/MS. In addition, a fully validated HPLC method was established to determine the contents of alpha-terthienyl in Radix Echinopsis. The contents ranged from 2.7 to 5.2 mg/g for five tested samples. The methods in this paper were simple and reliable, and could be used for the comprehensive quality control of Radix Echinopsis.

语种: 英语
所属项目编号: 985-2-119-121
项目资助者: Peking University
WOS记录号: WOS:000276573800010
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/61515
Appears in Collections:北京大学药学院_期刊论文

Files in This Item:

There are no files associated with this item.


作者单位: Peking Univ, State Key Lab Nat & Biomimet Drugs, Sch Pharmaceut Sci, Beijing 100191, Peoples R China

Recommended Citation:
Qiao, Xue,Han, Jian,He, Wen-ni,et al. Chemical fingerprint of commercial Radix Echinopsis and quantitative analysis of alpha-terthienyl[J]. JOURNAL OF SEPARATION SCIENCE,2010,33(4-5):530-538.
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[Qiao, Xue]'s Articles
[Han, Jian]'s Articles
[He, Wen-ni]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[Qiao, Xue]‘s Articles
[Han, Jian]‘s Articles
[He, Wen-ni]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit
所有评论 (0)
暂无评论
 
评注功能仅针对注册用户开放,请您登录
您对该条目有什么异议,请填写以下表单,管理员会尽快联系您。
内 容:
Email:  *
单位:
验证码:   刷新
您在IR的使用过程中有什么好的想法或者建议可以反馈给我们。
标 题:
 *
内 容:
Email:  *
验证码:   刷新

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Copyright © 2007-2017  北京大学医学部 - Feedback
Powered by CSpace