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学科主题: 临床医学
题名:
Renal plasmacytoma: Report of a rare case and review of the literature
作者: Zhang, Shi-Qiang1,2,3,4; Dong, Pei1; Zhang, Zhi-Ling1; Wu, Song1,4; Guo, Sheng-Jie1; Yao, Kai1; Li, Yong-Hong1; Liu, Zhuo-Wei1; Han, Hui1; Qin, Zi-Ke4; Cai, Zhi-Ming4; Li, Xian-Xin3; Zhou, Fang-Jian1
关键词: extramedullary plasmacytoma ; kidney ; multiple myeloma
刊名: ONCOLOGY LETTERS
发表日期: 2013-06-01
DOI: 10.3892/ol.2013.1282
卷: 5, 期:6, 页:1839-1843
收录类别: SCI
文章类型: Review
WOS标题词: Science & Technology
类目[WOS]: Oncology
研究领域[WOS]: Oncology
关键词[WOS]: SOLITARY EXTRAMEDULLARY PLASMACYTOMA ; KIDNEY
英文摘要:

Renal plasmacytoma is extremely rare, presenting diagnostic challenges due to its unusual location and non-specific or absent symptoms. To the best of our knowledge, only 24 cases of renal plasmacytoma have been reported in the literature. The present study reports a case of primary renal plasmacytoma in a 46-year-old female patient. Computed tomography (CT) revealed that the mass was located in the lower pole of the left kidney and metastasis was detected in an enlarged para-aortic lymph node. Following careful preparation, a partial nephrectomy was performed and the retroperitoneal lymph node was resected. A pathological examination revealed a renal parenchyma with lymph node involvement; this was confirmed by immunohistochemistry and nested polymerase chain reaction (PCR). Consequently, a diagnosis of a renal extramedullary plasmacytoma (EMP) was proposed. Following this unexpected diagnosis, various examinations were performed, but there was no evidence of systemic plasma cell disease. The patient refused further therapy, including external beam radiotherapy and chemotherapy. Abdominal CT was performed three months post-surgery and did not reveal any relapse. The patient remains disease-free at nine months post-surgery. The current study also presents a review of the literature. Although the general prognosis and outcome of EMP is good, a follow-up examination is recommended due to the possibility of relapse or progression to plasma cell neoplasm (PCN).

语种: 英语
所属项目编号: CXC201005260001A
项目资助者: Biobank of Complex Diseases in Shenzhen, China
WOS记录号: WOS:000324816500017
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/61543
Appears in Collections:北京大学深圳医院_泌尿外科_期刊论文

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作者单位: 1.Anhui Med Univ, Hefei 230022, Anhui, Peoples R China
2.Sun Yat Sen Univ, Ctr Canc, Dept Urol, State Key Lab Oncol Southern China, Guangzhou 510060, Guangdong, Peoples R China
3.Peking Univ, Shenzhen Hosp, Dept Urol, Shenzhen 518036, Guangdong, Peoples R China
4.Shenzhen Univ, Affiliated Hosp 1, Shenzhen Peoples Hosp 2, Shenzhen 518035, Guangdong, Peoples R China

Recommended Citation:
Zhang, Shi-Qiang,Dong, Pei,Zhang, Zhi-Ling,et al. Renal plasmacytoma: Report of a rare case and review of the literature[J]. ONCOLOGY LETTERS,2013,5(6):1839-1843.
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