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学科主题临床医学
Early Spatiotemporal Progress of Myelinated Nerve Fiber Regenerating through Biological Chitin Conduit after Injury
Zhang, Cheng; Zhang, Peixun; Wang, Yanhua; Yu, Kai; Kou, Yuhui; Jiang, Baoguo
关键词Peripheral nerve regeneration conduit Schwann cell axon rats
刊名ARTIFICIAL CELLS BLOOD SUBSTITUTES AND BIOTECHNOLOGY
2010-04-01
DOI10.3109/10731191003634836
38期:2页:103-108
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Biotechnology & Applied Microbiology ; Engineering, Biomedical ; Materials Science, Biomaterials
研究领域[WOS]Biotechnology & Applied Microbiology ; Engineering ; Materials Science
关键词[WOS]PERIPHERAL-NERVE ; SCIATIC-NERVE ; SCHWANN-CELLS ; SMALL-GAP ; AXONS ; DEGENERATION ; RATS ; MECHANISMS ; COLLAGEN ; DEFECT
英文摘要

Chitin conduits to bridge nerve injuries with a small gap (2mm) give us a biological window in which the peripheral nerve regeneration process can be observed. In this study, the regeneration process was observed on different intervals postoperatively. Histological analysis revealed that the early regeneration process occurred in three phase: degeneration and matrix phase, axonal and Schwann migration phase, myelination and maturation phase. Schwann cells grew into the lumen from both the proximal and distal nerve segments. Axonal regrowth progressed at an average rate of 1.4 mm/d. Regenerating axonal fibers were myelinated by Schwann cells from both sides of the conduit.

语种英语
WOS记录号WOS:000275467100007
项目编号30625036 ; 2005CB522604 ; 30801169 ; A-2008-10 ; 20070001780
资助机构Chinese National Science Fund for Outstanding Youth ; Chinese 973 Project Planning ; Chinese National Natural Science Youth Fund ; Beijing City Science and Technology New Star Classification ; Chinese ministry of education for Doctor Position New Teacher
引用统计
被引频次:11[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/61590
专题北京大学第二临床医学院
北京大学第二临床医学院_创伤骨科
北京大学第二临床医学院_党委院长办公室
北京大学第一临床医学院_呼吸科
作者单位Peking Univ, Peoples Hosp, Dept Trauma & Orthoped, Beijing 100044, Peoples R China
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GB/T 7714
Zhang, Cheng,Zhang, Peixun,Wang, Yanhua,et al. Early Spatiotemporal Progress of Myelinated Nerve Fiber Regenerating through Biological Chitin Conduit after Injury[J]. ARTIFICIAL CELLS BLOOD SUBSTITUTES AND BIOTECHNOLOGY,2010,38(2):103-108.
APA Zhang, Cheng,Zhang, Peixun,Wang, Yanhua,Yu, Kai,Kou, Yuhui,&Jiang, Baoguo.(2010).Early Spatiotemporal Progress of Myelinated Nerve Fiber Regenerating through Biological Chitin Conduit after Injury.ARTIFICIAL CELLS BLOOD SUBSTITUTES AND BIOTECHNOLOGY,38(2),103-108.
MLA Zhang, Cheng,et al."Early Spatiotemporal Progress of Myelinated Nerve Fiber Regenerating through Biological Chitin Conduit after Injury".ARTIFICIAL CELLS BLOOD SUBSTITUTES AND BIOTECHNOLOGY 38.2(2010):103-108.
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