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学科主题临床医学
Preliminary study of whole-body diffusion-weighted imaging in detecting pulmonary metastatic lesions from clear cell renal cell carcinoma: comparison with CT
Liu, Jing; Yang, Xuedong; Li, Feiyu; Wang, Xiaoying; Jiang, Xuexiang
关键词Whole-body diffusion-weighted imaging (DWI) renal cell carcinoma (RCC) pulmonary metastases
刊名ACTA RADIOLOGICA
2011-11-01
DOI10.1258/ar.2011.110121
52期:9页:954-963
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Radiology, Nuclear Medicine & Medical Imaging
研究领域[WOS]Radiology, Nuclear Medicine & Medical Imaging
关键词[WOS]POSITRON-EMISSION-TOMOGRAPHY ; SCINTIGRAPHY ; LUNG ; MRI
英文摘要

Background: Whole-body diffusion-weighted imaging (DWI) has been widely used in detecting malignant metastases, including pulmonary metastases.

Purpose: To evaluate the possible utility of whole-body DWI in detecting pulmonary metastases of patients with clear cell renal cell carcinoma (ccRCC) and compare the exact differences between MR and CT in detecting pulmonary lesions.

Material and Methods: Whole-body DWI and chest CT examinations were performed on nine consecutive patients (8 men and 1 woman) with histologically confirmed ccRCC and possible metastatic lesions before chemotherapy.

Results: CT and MR demonstrated pulmonary metastases in seven patients and no metastatic lesions in two patients. The numbers of pulmonary metastases detected on CT, DWI-only, T1WI-only and DWI in combination with T1WI were 83, 35, 34 and 39, respectively. Metastases with a diameter above 1.0 cm could all be detected by DWI and a diameter above 0.7 cm could all be detected by DWI in combination with T1WI. Significant differences were obtained both for correlationship between diameter and detection rates of DWI and T1WI by using Spearman rank correlation analysis.

Conclusion: Although MR cannot be considered a replacement for CT in pulmonary metastases from ccRCC, whole-body DWI, with the combination of T1 dual echo, might be helpful for the evaluation of tumor response to chemotherapy in the follow-up of patients when the diameter of the pulmonary metastases is over 1.0 cm.

语种英语
WOS记录号WOS:000297489200004
Citation statistics
Cited Times:8[WOS]   [WOS Record]     [Related Records in WOS]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/61594
Collection北京大学第一临床医学院_放射治疗科
作者单位Peking Univ, Hosp 1, Dept Radiol, Beijing 100871, Peoples R China
Recommended Citation
GB/T 7714
Liu, Jing,Yang, Xuedong,Li, Feiyu,et al. Preliminary study of whole-body diffusion-weighted imaging in detecting pulmonary metastatic lesions from clear cell renal cell carcinoma: comparison with CT[J]. ACTA RADIOLOGICA,2011,52(9):954-963.
APA Liu, Jing,Yang, Xuedong,Li, Feiyu,Wang, Xiaoying,&Jiang, Xuexiang.(2011).Preliminary study of whole-body diffusion-weighted imaging in detecting pulmonary metastatic lesions from clear cell renal cell carcinoma: comparison with CT.ACTA RADIOLOGICA,52(9),954-963.
MLA Liu, Jing,et al."Preliminary study of whole-body diffusion-weighted imaging in detecting pulmonary metastatic lesions from clear cell renal cell carcinoma: comparison with CT".ACTA RADIOLOGICA 52.9(2011):954-963.
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