|The Influence of Kyphosis Correction Surgery on Pulmonary Function and Thoracic Volume|
|Zeng, Yan1; Chen, Zhongqiang1; Ma, Desi1; Guo, Zhaoqing1; Qi, Qiang1; Li, Weishi1; Sun, Chuiguo1; Liu, Ning1; White, Andrew P.2|
|关键词||kyphosis posterior corrective surgery pulmonary function thoracic volume|
|WOS标题词||Science & Technology|
|类目[WOS]||Clinical Neurology ; Orthopedics|
|研究领域[WOS]||Neurosciences & Neurology ; Orthopedics|
|关键词[WOS]||ANKYLOSING-SPONDYLITIS ; HUMAN-LUNG ; POSTNATAL-DEVELOPMENT ; IDIOPATHIC SCOLIOSIS ; GROWTH ; IMPROVEMENT ; EXPANSION ; DEFORMITY ; RESECTION ; CHILDREN|
Study Design. A clinical study.
Objective. To measure the changes in pulmonary function and thoracic volume associated with surgical correction of kyphotic deformities.
Summary of Background Data. No prior study has focused on the pulmonary function and thoracic cavity volume before and after corrective surgery for kyphosis.
Methods. Thirty-four patients with kyphosis underwent posterior deformity correction with instrumented fusion. Preoperative and postoperative pulmonary function was measured, and pulmonary function grade was evaluated as mild, significant, or severe. The change in preoperative to postoperative pulmonary function was analyzed, using 6 comparative subgroupings of patients on the basis of age, severity of kyphosis, location of kyphosis apex, length of follow-up time after surgery, degree of kyphosis correction, and number of segments fused. A second group of 19 patients also underwent posterior surgical correction of kyphosis, which had thoracic volume measured preoperatively and postoperatively with computed tomographic scanning.
Results. All of the pulmonary impairments were found to be restrictive. After surgery, most of the patients had improvement of the pulmonary function. Before surgery, the pulmonary function differences were found to be significant based on both severity of preoperative kyphosis (<60 degrees vs. >60 degrees) and location of the kyphosis apex (above T10 vs. below T10). Younger patients (younger than 35 yr) were more likely to exhibit statistically significant improvements in pulmonary function after surgery. However, thoracic volume was not significantly related to pulmonary function parameters. After surgery, average thoracic volume had no significant change.
Conclusion. The major pulmonary impairment caused by kyphosis was found to be restrictive. Patients with kyphosis angle of 60 degrees or greater or with kyphosis apex above T10 had more severe pulmonary dysfunction. Patients′ age was significantly related to change in pulmonary function after surgery. However, the average thoracic volume had no significant change after surgery.
|作者单位||1.Harvard Univ, Sch Med, Boston, MA USA|
2.Peking Univ, Hosp 3, Dept Orthoped, Beijing 100191, Peoples R China
3.Beth Israel Deaconess Med Ctr, Carl J Shapiro Dept Orthopaed Surg, Boston, MA 02215 USA
|Zeng, Yan,Chen, Zhongqiang,Ma, Desi,et al. The Influence of Kyphosis Correction Surgery on Pulmonary Function and Thoracic Volume[J]. SPINE,2014,39(21):1777-1784.|
|APA||Zeng, Yan.,Chen, Zhongqiang.,Ma, Desi.,Guo, Zhaoqing.,Qi, Qiang.,...&White, Andrew P..(2014).The Influence of Kyphosis Correction Surgery on Pulmonary Function and Thoracic Volume.SPINE,39(21),1777-1784.|
|MLA||Zeng, Yan,et al."The Influence of Kyphosis Correction Surgery on Pulmonary Function and Thoracic Volume".SPINE 39.21(2014):1777-1784.|