IR@PKUHSC  > 北京大学第三临床医学院
学科主题临床医学
Evaluating perfusion of thoracic spinal cord blood using CEUS during thoracic spinal stenosis decompression surgery
Ling, J.1; Jinrui, W.1; Ligang, C.1; Wen, C.1; Xiaoguang, L.2; Liang, J.2
刊名SPINAL CORD
2015-03-01
DOI10.1038/sc.2014.213
53期:3页:195-199
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Clinical Neurology ; Rehabilitation
研究领域[WOS]Neurosciences & Neurology ; Rehabilitation
关键词[WOS]INJURY ; FLOW ; COMPRESSION ; ULTRASONOGRAPHY
英文摘要

Study design: A clinical study in human spinal cord.

Objectives: To evaluate changes in spinal cord blood perfusion in patients with thoracic spinal stenosis using contrast-enhanced ultrasonography and to semiquantitatively analyze blood perfusion changes in compressed spinal cord before and after ventral decompression.

Setting: Ultrasound department of a university hospital.

Methods: Twelve patients with confirmed thoracic spinal stenosis who needed decompression surgery participated. They underwent an intravenous injection of a contrast agent before and after ventral decompression. Quantitative analysis software (Philips Healthcare, Bothell, WA, USA) was used to perform time-intensity curve (TIC) analysis. The enhanced intensity (Delta I), rise time (Delta T) and slope of the TIC (beta) were separately calculated; t-tests of the independent samples were performed on the indicators.

Results: The TICs showed no significant differences between compressed spinal cord and normal spinal cord Delta T, enhanced Delta I and beta (P = 0.46, P = 0.23 and P = 0.16, respectively). After ventral decompression, Delta I of the originally compressed spinal cord increased substantially (P = 0.04) compared with Delta I of the normal spinal cord; however, the Delta T and beta showed no significant differences (P = 0.18 and P = 0.09, respectively). Comparison of the blood perfusion parameters (that is, Delta T and Delta I) of the compressed spinal cords before and after ventral decompression showed no significant differences (P = 0.14 and P = 0.12, respectively), but beta showed significant difference (P = 0.02).

Conclusion: Contrast-enhanced ultrasonography can dynamically display spinal cord blood perfusion. The characteristics of blood perfusion can be semiquantitatively analyzed using a software technique.

语种英语
WOS记录号WOS:000350797900006
Citation statistics
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/61720
Collection北京大学第三临床医学院
作者单位1.Peking Univ, Hosp 3, Ultrasound Diag Dept, Beijing 100191, Peoples R China
2.Peking Univ, Hosp 3, Dept Osteol, Beijing 100191, Peoples R China
Recommended Citation
GB/T 7714
Ling, J.,Jinrui, W.,Ligang, C.,et al. Evaluating perfusion of thoracic spinal cord blood using CEUS during thoracic spinal stenosis decompression surgery[J]. SPINAL CORD,2015,53(3):195-199.
APA Ling, J.,Jinrui, W.,Ligang, C.,Wen, C.,Xiaoguang, L.,&Liang, J..(2015).Evaluating perfusion of thoracic spinal cord blood using CEUS during thoracic spinal stenosis decompression surgery.SPINAL CORD,53(3),195-199.
MLA Ling, J.,et al."Evaluating perfusion of thoracic spinal cord blood using CEUS during thoracic spinal stenosis decompression surgery".SPINAL CORD 53.3(2015):195-199.
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