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学科主题: 药学
题名:
A new bufadienolide obtained from the biotransformation of cinobufagin by Alternaria alternata
作者: Ye, Min; Guo, Dean
关键词: Alternaria alternata ; biotransformation ; bufadienolide ; cinobufagin ; cytotoxicity ; 12-oxo-desacetylcinobufagin
刊名: NATURAL PRODUCT RESEARCH
发表日期: 2008
DOI: 10.1080/14786410601130141
卷: 22, 期:1, 页:26-30
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Chemistry, Applied ; Chemistry, Medicinal
研究领域[WOS]: Chemistry ; Pharmacology & Pharmacy
关键词[WOS]: HUMAN LEUKEMIA-CELLS ; CYTOTOXIC BUFADIENOLIDES ; MICROBIAL HYDROXYLATION ; CATHARANTHUS-ROSEUS ; BUFALIN ; 12-BETA-HYDROXYLATION ; PLANT
英文摘要:

A new bufadienolide, 12-oxo-desacetylcinobufagin, was obtained from the biotransformation of cinobufagin by Alternaria alternata in fairly low yield (0.34%). Its structure was established on the basis of H-1-NMR, C-13-NMR, 2D-NMR, and MS spectral data.

语种: 英语
WOS记录号: WOS:000252342100004
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/61745
Appears in Collections:北京大学药学院_期刊论文

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作者单位: Peking Univ, Sch Pharmaceut Sci, State Key Lab Nat & Biomimet Drugs, Beijing 100083, Peoples R China

Recommended Citation:
Ye, Min,Guo, Dean. A new bufadienolide obtained from the biotransformation of cinobufagin by Alternaria alternata[J]. NATURAL PRODUCT RESEARCH,2008,22(1):26-30.
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