IR@PKUHSC  > 北京大学基础医学院  > 病理学系
学科主题基础医学
A study on psammoma body mineralization in meningiomas
Wang, Changqiu1; Yang, Ruochen1,3; Li, Ya1; Xiong, Cuie1; Zhao, Wenwen1; Liu, Jianying2; Zhang, Bo2; Lu, Anhuai1
关键词Biomineralization Meningioma Psammoma body Pathological mineralization
刊名JOURNAL OF MINERALOGICAL AND PETROLOGICAL SCIENCES
2011-10-01
DOI10.2465/jmps.110310
106期:5页:229-234
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Mineralogy
资助者National Basic Research Program of China (973 Program) ; National Natural Science Foundation of China ; National Basic Research Program of China (973 Program) ; National Natural Science Foundation of China
研究领域[WOS]Mineralogy
关键词[WOS]SCANNING ELECTRON-MICROSCOPY ; BREAST ; MICROCALCIFICATIONS ; BODIES ; BONE ; BIOMINERALIZATION ; EXPRESSION ; COLLAGEN ; CALCIUM
英文摘要

Psammoma bodies (PBs) in meningioma patients often contain mineral deposits. In this paper, the mineralogical characteristics of PBs in the mineralized focus in meningioma patients were investigated by using scanning electron microscopy (SEM), environmental scanning electron microscopy (ESEM), high-resolution transmission electron microscopy (HRTEM), energy dispersive X-ray analysis (EDAX), and electron probe microanalysis (EPMA). We found that PBs had a concentric layered structure and the size ranged from several to tens of micrometers. Although no obvious trend in the variation of Ca/P ratios was observed from the center to the outer edge of the PBs, the Ca/P ratios were much lower in the early stage of PBs formation. The concentric layered structure of the Pas might be formed by a spiral arrangement of mineralized collagen fibers. Studies on PBs mineralization may provide some supporting information in understanding the origin and development of meningiomas.

语种英语
所属项目编号2007CB8 15602 ; 40872196
资助者National Basic Research Program of China (973 Program) ; National Natural Science Foundation of China ; National Basic Research Program of China (973 Program) ; National Natural Science Foundation of China
WOS记录号WOS:000296797300001
Citation statistics
文献类型期刊论文
版本出版稿
条目标识符http://ir.bjmu.edu.cn/handle/400002259/61768
Collection北京大学基础医学院_病理学系
作者单位1.China Minerals Corp, Beijing 100044, Peoples R China
2.Peking Univ, Sch Earth & Space Sci, MOE, Key Lab Orogen Belts & Crustal Evolut, Beijing 100871, Peoples R China
3.Peking Univ, Hlth Sci Ctr, Sch Basic Med Sci, Dept Pathol, Beijing 100083, Peoples R China
Recommended Citation
GB/T 7714
Wang, Changqiu,Yang, Ruochen,Li, Ya,et al. A study on psammoma body mineralization in meningiomas[J]. JOURNAL OF MINERALOGICAL AND PETROLOGICAL SCIENCES,2011,106(5):229-234.
APA Wang, Changqiu.,Yang, Ruochen.,Li, Ya.,Xiong, Cuie.,Zhao, Wenwen.,...&Lu, Anhuai.(2011).A study on psammoma body mineralization in meningiomas.JOURNAL OF MINERALOGICAL AND PETROLOGICAL SCIENCES,106(5),229-234.
MLA Wang, Changqiu,et al."A study on psammoma body mineralization in meningiomas".JOURNAL OF MINERALOGICAL AND PETROLOGICAL SCIENCES 106.5(2011):229-234.
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