|Risk factors and in-hospital mortality in Chinese patients undergoing coronary artery bypass grafting: Analysis of a large multi-institutional Chinese database|
|Zheng, Zhe1,2; Zhang, Lu1,2; Hu, Shengshou1,2; Li, Xi3; Yuan, Xin1,2; Gao, Huawei1,2; Chinese Cardiovasc Surgical Regist|
|刊名||JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY|
|WOS标题词||Science & Technology|
|类目[WOS]||Cardiac & Cardiovascular Systems ; Respiratory System ; Surgery|
|研究领域[WOS]||Cardiovascular System & Cardiology ; Respiratory System ; Surgery|
|关键词[WOS]||OPERATIVE RISK ; SURGERY ; EUROSCORE|
Objective: This study was undertaken to delineate outcomes and to assess risk factors for in-hospital mortality among Chinese patients undergoing coronary artery bypass grafting.
Methods: From 2007 to 2008, a total of 9838 consecutive adult patients undergoing coronary artery bypass grafting were enrolled in the Chinese Coronary Artery Bypass Grafting Registry, which included 43 centers from 17 province-level regions in China. This registry collected information on 67 preoperative factors and 30 operative factors believed to influence in-hospital mortality. The relationship between risk factors and in-hospital mortality was evaluated by univariate and logistic regression analyses.
Results: Overall in-hospital mortality was 2.5%. Eleven risk factors were found to be significant predictors for outcome: age (continuous), body mass index (continuous), left ventricular ejection fraction (continuous), preoperative New York Heart Association functional class III or IV, chronic renal failure, extracardiac arteriopathy, chronic obstructive pulmonary disease, preoperative atrial fibrillation or flutter (within 2 weeks), preoperative critical state, other than elective surgery, and combined valve procedure. Calibration with the Hosmer-Lemeshow test was satisfactory (P=.35), and the discrimination power was good (area under the receiver operating characteristic curve, 0.81; 95% confidence interval, 0.79-0.84).
Conclusions: The risk profiles and in-hospital mortality of Chinese patients undergoing coronary artery bypass grafting were determined from data in the most up-to-date multi-institutional database. Eleven variables were demonstrated to be independent risk factors for in-hospital death after coronary artery bypass grafting. (J Thorac Cardiovasc Surg 2012;144:355-9)
|项目编号||200902001 ; 2006BAI01A09|
|资助机构||Public Specialty Fund of Health Ministry ; Key Project in the National Science and Technology Pillar Program ; National Public Scientific Institute|
|作者单位||1.Chinese Acad Med Sci, Beijing 100730, Peoples R China|
2.Peking Union Med Coll, Fuwai Hosp, Dept Cardiovasc Surg, State Key Lab Cardiovasc Dis,Fuwai Hosp, Beijing 100021, Peoples R China
3.Peking Univ, Hlth Sci Ctr, Sch Publ Hlth, Dept Epidemiol & Biostat, Beijing 100871, Peoples R China
|Zheng, Zhe,Zhang, Lu,Hu, Shengshou,et al. Risk factors and in-hospital mortality in Chinese patients undergoing coronary artery bypass grafting: Analysis of a large multi-institutional Chinese database[J]. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY,2012,144(2):355-+.|
|APA||Zheng, Zhe.,Zhang, Lu.,Hu, Shengshou.,Li, Xi.,Yuan, Xin.,...&Chinese Cardiovasc Surgical Regist.(2012).Risk factors and in-hospital mortality in Chinese patients undergoing coronary artery bypass grafting: Analysis of a large multi-institutional Chinese database.JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY,144(2),355-+.|
|MLA||Zheng, Zhe,et al."Risk factors and in-hospital mortality in Chinese patients undergoing coronary artery bypass grafting: Analysis of a large multi-institutional Chinese database".JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY 144.2(2012):355-+.|