|Diagnostic value of endobronchial ultrasound guided transbronchial needle aspiration in superior vena cava syndrome|
|Zhou Zu-li1; Zhao Hui1; Li Yun1; Sui Xi-zhao1; Xie Zhen1; Chen Ke-zhong1; Yang Feng1; Li Feng-wei3; Liu Jun1; Zheng Hong-fang2; Wang Jun1|
|关键词||endobronchial ultrasound transbronchial needle aspiration superior vena cava syndrome diagnosis|
|刊名||CHINESE MEDICAL JOURNAL|
|WOS标题词||Science & Technology|
|类目[WOS]||Medicine, General & Internal|
|研究领域[WOS]||General & Internal Medicine|
|关键词[WOS]||CELL LUNG-CANCER ; MEDIASTINOSCOPY STILL ; GOLD STANDARD ; LYMPH-NODES ; OBSTRUCTION ; CARCINOMA|
Background The pathological diagnosis is of critical importance to the subsequent treatment for the pathients with superior vena cave syndrome (SVCS). The aim of this study is to report our experience in the diagnosis of SVCS by endobronchial ultrasound guided transbronchial needle aspiration (EBUS-TBNA).
Methods The data of 520 patients who underwent EBUS-TBNA from September 2009 to May 2012 at our institution were reviewed. Of these, there were 14 males and 6 females (mean age of 59.1 years) with SVCS who received EBUS-TBNA that were included in the analysis.
Results The mean short axis diameter of the paratracheal lesions was (3.32 +/- 1.79) cm (range, 1.69 to 9.50 cm) and 6 cases also had subcarinal lymph node enlargement with a mean short axis diameter of (2.14 +/- 0.49) cm (range, 1.73 to 3.01 cm). An average of 4.3 punctures was performed per lesion. Malignancy was confirmed in 16 cases (10 small cell carcinomas, 4 adenocarcinomas, 1 squamous cell carcinoma and 1 Hodgkin lymphoma). In two patients, pathological examination of tissue revealed no evidence of malignancy and for 13 to 24 months of follow-up. One patient from whom adequate tissue was not obtained refused further surgical biopsy since he had undergone endovascular stenting of the SVC. One patient in whom a diagnosis was not obtained by EBUS-TBNA underwent thoracoscopic biopsy and the final diagnosis was B cell non-Hodgkin′s lymphoma. The diagnosis accuracy of EBUS-TBNA in SVCS was 18/20 patients.
Conclusion EBUS-TBNA is a highly effective and safe procedure for the diagnosis of SVCS.
|作者单位||1.Peking Univ, Peoples Hosp, Dept Thorac Surg, Beijing 100044, Peoples R China|
2.Peking Univ, Peoples Hosp, Dept Pathol, Beijing 100044, Peoples R China
3.Beijing Aerosp Hosp, Dept Thorac Surg, Beijing 100076, Peoples R China
|Zhou Zu-li,Zhao Hui,Li Yun,et al. Diagnostic value of endobronchial ultrasound guided transbronchial needle aspiration in superior vena cava syndrome[J]. CHINESE MEDICAL JOURNAL,2013,126(23):4453-4456.|
|APA||Zhou Zu-li.,Zhao Hui.,Li Yun.,Sui Xi-zhao.,Xie Zhen.,...&Wang Jun.(2013).Diagnostic value of endobronchial ultrasound guided transbronchial needle aspiration in superior vena cava syndrome.CHINESE MEDICAL JOURNAL,126(23),4453-4456.|
|MLA||Zhou Zu-li,et al."Diagnostic value of endobronchial ultrasound guided transbronchial needle aspiration in superior vena cava syndrome".CHINESE MEDICAL JOURNAL 126.23(2013):4453-4456.|