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A Meta-Analysis of Acupuncture Combined with Opioid Receptor Agonists for Treatment of Opiate-Withdrawal Symptoms
Liu, Ting-ting1; Shi, Jie1; Epstein, David H.2; Bao, Yan-ping1; Lu, Lin1
关键词Acupuncture Opioid Detoxification Meta-analysis
刊名CELLULAR AND MOLECULAR NEUROBIOLOGY
2009-06-01
DOI10.1007/s10571-008-9336-4
29期:4页:449-454
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Cell Biology ; Neurosciences
研究领域[WOS]Cell Biology ; Neurosciences & Neurology
关键词[WOS]RANDOMIZED CONTROLLED-TRIAL ; ADDICTION ; MORPHINE ; RATS ; ELECTROACUPUNCTURE ; TOLERANCE ; NUCLEUS ; HEROIN
英文摘要

This review extends a prior meta-analysis of acupuncture′s utility for treating opioid detoxification, addressing the efficacy of acupuncture when combined with allopathic therapies. Both English and Chinese databases were searched for randomized trials comparing acupuncture combined with opioid agonist treatment versus opioid agonists alone for treating symptoms of opioid withdrawal. The methodological quality of each study was assessed with Jadad′s scale (1-2 = low; 3-5 = high). Meta-analysis was performed with fixed- or random-effect models in RevMan software; the outcome measures assessed were withdrawal-symptoms score, relapse rate, side effects, and medication dosage. Withdrawal-symptom scores were lower in combined treatment trials than in agonist-alone trials on withdrawal days 1, 7, 9, and 10. Combined treatment also produced lower reported rates of side effects and appeared to lower the required dose of opioid agonist. There was no significant difference on relapse rate after 6 months. This meta-analysis suggests that acupuncture combined with opioid agonists can effectively be used to manage the withdrawal symptoms. One limitation of this meta-analysis is the poor quality of the methodology of some included trials. High-quality studies are needed to confirm findings regarding the side effects and medication dosage.

语种英语
WOS记录号WOS:000266921200004
引用统计
被引频次:16[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/61990
专题北京大学第三临床医学院_总务处
中国药物依赖性研究所
作者单位1.Peking Univ, Natl Inst Drug Dependence, Beijing 100083, Peoples R China
2.NIDA, Intramural Res Program, NIH, Baltimore, MD 21224 USA
推荐引用方式
GB/T 7714
Liu, Ting-ting,Shi, Jie,Epstein, David H.,et al. A Meta-Analysis of Acupuncture Combined with Opioid Receptor Agonists for Treatment of Opiate-Withdrawal Symptoms[J]. CELLULAR AND MOLECULAR NEUROBIOLOGY,2009,29(4):449-454.
APA Liu, Ting-ting,Shi, Jie,Epstein, David H.,Bao, Yan-ping,&Lu, Lin.(2009).A Meta-Analysis of Acupuncture Combined with Opioid Receptor Agonists for Treatment of Opiate-Withdrawal Symptoms.CELLULAR AND MOLECULAR NEUROBIOLOGY,29(4),449-454.
MLA Liu, Ting-ting,et al."A Meta-Analysis of Acupuncture Combined with Opioid Receptor Agonists for Treatment of Opiate-Withdrawal Symptoms".CELLULAR AND MOLECULAR NEUROBIOLOGY 29.4(2009):449-454.
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