|Early growth of preterm infants with prolonged hospitalisation|
|Ru, Xi-Fang; Feng, Qi; Wang, Ying; Zhang, Xin; Li, Xing; Meng, Jing-Wen; Guo, Zai-Chen|
|关键词||body weight Z-score follow-up growth infant preterm underweight|
|刊名||SINGAPORE MEDICAL JOURNAL|
|WOS标题词||Science & Technology|
|类目[WOS]||Medicine, General & Internal|
|研究领域[WOS]||General & Internal Medicine|
|关键词[WOS]||LOW-BIRTH-WEIGHT ; EXTREMELY PREMATURE-INFANTS ; CORONARY-HEART-DISEASE ; INTENSIVE-CARE-UNIT ; CATCH-UP GROWTH ; POSTDISCHARGE GROWTH ; GESTATIONAL-AGE ; CARDIOVASCULAR-DISEASE ; BODY-COMPOSITION ; FETAL ORIGINS|
INTRODUCTION This study aimed to determine the early growth patterns of preterm infants who required prolonged hospitalisation in terms of body weight Z-score, and to explore the influencing factors and predictors of their growth.
METHODS The criteria of enrolment included preterm birth, singleton pregnancy, hospitalisation within the first 24 hours of life, hospital stay >= 28 days and clinical follow-up beyond 91 days of corrected age. Body weight Z-scores and the incidence of underweight infants were reviewed periodically, and the influencing factors and possible predictors of growth analysed.
RESULTS Body weight Z-scores of all infants of gestational age (GA) groups kept decreasing, with a trough seen at 36 weeks corrected gestational age (CGA). At corrected full-term, body weight Z-scores for all birth weight groups achieved birth level and were higher than that at 36 weeks CGA. Body weight Z-scores at 61 days corrected age was (-0.300 x GA [weeks] + 0.210 x birth weight [g] + 0.682 x body weight Z-score) at 40 weeks CGA. The cut-off values for body weight Z-score at birth (cut-off, -1.79; sensitivity, 100%; specificity, 91.3%) and 61 days corrected age (cut-off, -1.95; sensitivity, 100%; specificity, 97.1%) were selected to predict the risk of being underweight at 183 days corrected age.
CONCLUSION Early growth restriction is a practical problem in preterm infants with prolonged hospitalisation. Body weight Z-scores at 40 weeks CGA and 61 days corrected age can be used to predict body weight gain prior to 183 days corrected age in these infants.
|资助机构||Grants of Developmental Origins of Health and Disease (DOHaD), China|
|作者单位||Peking Univ, Dept Paediat, Hosp 1, Beijing 100034, Peoples R China|
|Ru, Xi-Fang,Feng, Qi,Wang, Ying,et al. Early growth of preterm infants with prolonged hospitalisation[J]. SINGAPORE MEDICAL JOURNAL,2012,53(12):832-839.|
|APA||Ru, Xi-Fang.,Feng, Qi.,Wang, Ying.,Zhang, Xin.,Li, Xing.,...&Guo, Zai-Chen.(2012).Early growth of preterm infants with prolonged hospitalisation.SINGAPORE MEDICAL JOURNAL,53(12),832-839.|
|MLA||Ru, Xi-Fang,et al."Early growth of preterm infants with prolonged hospitalisation".SINGAPORE MEDICAL JOURNAL 53.12(2012):832-839.|