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学科主题临床医学
Early growth of preterm infants with prolonged hospitalisation
Ru, Xi-Fang; Feng, Qi; Wang, Ying; Zhang, Xin; Li, Xing; Meng, Jing-Wen; Guo, Zai-Chen
关键词body weight Z-score follow-up growth infant preterm underweight
刊名SINGAPORE MEDICAL JOURNAL
2012-12-01
53期:12页:832-839
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Medicine, General & Internal
研究领域[WOS]General & Internal Medicine
关键词[WOS]LOW-BIRTH-WEIGHT ; EXTREMELY PREMATURE-INFANTS ; CORONARY-HEART-DISEASE ; INTENSIVE-CARE-UNIT ; CATCH-UP GROWTH ; POSTDISCHARGE GROWTH ; GESTATIONAL-AGE ; CARDIOVASCULAR-DISEASE ; BODY-COMPOSITION ; FETAL ORIGINS
英文摘要

INTRODUCTION This study aimed to determine the early growth patterns of preterm infants who required prolonged hospitalisation in terms of body weight Z-score, and to explore the influencing factors and predictors of their growth.

METHODS The criteria of enrolment included preterm birth, singleton pregnancy, hospitalisation within the first 24 hours of life, hospital stay >= 28 days and clinical follow-up beyond 91 days of corrected age. Body weight Z-scores and the incidence of underweight infants were reviewed periodically, and the influencing factors and possible predictors of growth analysed.

RESULTS Body weight Z-scores of all infants of gestational age (GA) groups kept decreasing, with a trough seen at 36 weeks corrected gestational age (CGA). At corrected full-term, body weight Z-scores for all birth weight groups achieved birth level and were higher than that at 36 weeks CGA. Body weight Z-scores at 61 days corrected age was (-0.300 x GA [weeks] + 0.210 x birth weight [g] + 0.682 x body weight Z-score) at 40 weeks CGA. The cut-off values for body weight Z-score at birth (cut-off, -1.79; sensitivity, 100%; specificity, 91.3%) and 61 days corrected age (cut-off, -1.95; sensitivity, 100%; specificity, 97.1%) were selected to predict the risk of being underweight at 183 days corrected age.

CONCLUSION Early growth restriction is a practical problem in preterm infants with prolonged hospitalisation. Body weight Z-scores at 40 weeks CGA and 61 days corrected age can be used to predict body weight gain prior to 183 days corrected age in these infants.

语种英语
WOS记录号WOS:000314455300018
资助机构Grants of Developmental Origins of Health and Disease (DOHaD), China
引用统计
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/62087
专题北京大学第一临床医学院_儿科
作者单位Peking Univ, Dept Paediat, Hosp 1, Beijing 100034, Peoples R China
推荐引用方式
GB/T 7714
Ru, Xi-Fang,Feng, Qi,Wang, Ying,et al. Early growth of preterm infants with prolonged hospitalisation[J]. SINGAPORE MEDICAL JOURNAL,2012,53(12):832-839.
APA Ru, Xi-Fang.,Feng, Qi.,Wang, Ying.,Zhang, Xin.,Li, Xing.,...&Guo, Zai-Chen.(2012).Early growth of preterm infants with prolonged hospitalisation.SINGAPORE MEDICAL JOURNAL,53(12),832-839.
MLA Ru, Xi-Fang,et al."Early growth of preterm infants with prolonged hospitalisation".SINGAPORE MEDICAL JOURNAL 53.12(2012):832-839.
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