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学科主题: 临床医学
题名:
Gas Injection versus Vitrectomy with Gas for Treating Retinal Detachment Owing to Macular Hole in High Myopes
作者: Li, Xiaoxin1; Wang, Wenji2; Tang, Shibo3; Zhao, Jialiang4
刊名: OPHTHALMOLOGY
发表日期: 2009-06-01
DOI: 10.1016/j.ophtha.2009.01.003
卷: 116, 期:6, 页:1182-1187
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Ophthalmology
研究领域[WOS]: Ophthalmology
关键词[WOS]: POSTERIOR STAPHYLOMA ; EPIRETINAL MEMBRANE ; EYES ; C3F8
英文摘要:

Objective: To compare the efficacy between intravitreal gas injection alone and pars plana vitrectomy (PPV) with intraocular gas tamponade in treating retinal detachment due to macular hole in high myopes.

Design: Prospective, randomized controlled, multicenter study.

Participants: We included 231 eyes of 231 patients with retinal detachment owing to myopic macular hole from 14 study sites in China.

Intervention: The patients were randomly assigned to undergo intravitreal perfluoropropane (C3F8) gas injection (group A) or vitrectomy with intraocular C3F8 gas tamponade (group B).

Main Outcome Measures: Complete ocular examination included best-corrected visual acuity, applanation tonometry, slit-lamp biomicroscopy, color fundus photography, ultrasound examination, and optical coherence tomography at baseline and every 3 months after the surgery.

Results: At 12 months after surgery, the retinal reattachment rates was 59.8% (52 eyes) in group A, which was significantly lower than group B (79 eyes, 74.5%; P = 0.029). Logistic regression showed that PPV (P<0.001) and low height of retinal detachment at baseline (P = 0.068) were associated with a greater retinal reattachment rate. Subgroup analysis revealed that in group B, concomitant internal limiting membrane (ILM) peeling showed a slightly higher anatomic success rate (79.2%) than no ILM peeling (70.0%). The postoperative best-corrected visual acuity of the eyes with attached retina between group A and B was not significantly different (P>0.05).

Conclusions: Pars plana vitrectomy with C3F8 endotamponade resulted in a higher anatomic success rate than intravitreal C3F8 gas injection alone in treating retinal detachment owing to macular hole in high myopes.

Financial Disclosure(s): The authors have no proprietary or commercial interest in any materials discussed in the article. Ophthalmology 2009;116:1182-1187 (C) 2009 by the American Academy of Ophthalmology.

语种: 英语
所属项目编号: 2004BA720A14 ; 2005CB724307
项目资助者: National "10th five-year plan" of Key Technologies RD Programme ; National Basic Research Program of China
WOS记录号: WOS:000266906500022
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/62101
Appears in Collections:北京大学第二临床医学院_眼科_期刊论文

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作者单位: 1.Peking Univ, Peoples Hosp, Dept Ophthalmol, Beijing 100044, Peoples R China
2.Eye Ear Nose Throat Hosp, Dept Ocular Fundus, Shanghai, Peoples R China
3.Sun Yat Sen Univ, Zhong Shan Ophthalm Ctr, Guangzhou 510275, Guangdong, Peoples R China
4.Peking Union Hosp, Peking Union Med Coll, Inst Eye, Beijing, Peoples R China

Recommended Citation:
Li, Xiaoxin,Wang, Wenji,Tang, Shibo,et al. Gas Injection versus Vitrectomy with Gas for Treating Retinal Detachment Owing to Macular Hole in High Myopes[J]. OPHTHALMOLOGY,2009,116(6):1182-1187.
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