IR@PKUHSC  > 北京大学第二临床医学院  > 眼科
学科主题临床医学
Gas Injection versus Vitrectomy with Gas for Treating Retinal Detachment Owing to Macular Hole in High Myopes
Li, Xiaoxin1; Wang, Wenji2; Tang, Shibo3; Zhao, Jialiang4
刊名OPHTHALMOLOGY
2009-06-01
DOI10.1016/j.ophtha.2009.01.003
116期:6页:1182-1187
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Ophthalmology
资助者National "10th five-year plan" of Key Technologies RD Programme ; National Basic Research Program of China ; National "10th five-year plan" of Key Technologies RD Programme ; National Basic Research Program of China
研究领域[WOS]Ophthalmology
关键词[WOS]POSTERIOR STAPHYLOMA ; EPIRETINAL MEMBRANE ; EYES ; C3F8
英文摘要

Objective: To compare the efficacy between intravitreal gas injection alone and pars plana vitrectomy (PPV) with intraocular gas tamponade in treating retinal detachment due to macular hole in high myopes.

Design: Prospective, randomized controlled, multicenter study.

Participants: We included 231 eyes of 231 patients with retinal detachment owing to myopic macular hole from 14 study sites in China.

Intervention: The patients were randomly assigned to undergo intravitreal perfluoropropane (C3F8) gas injection (group A) or vitrectomy with intraocular C3F8 gas tamponade (group B).

Main Outcome Measures: Complete ocular examination included best-corrected visual acuity, applanation tonometry, slit-lamp biomicroscopy, color fundus photography, ultrasound examination, and optical coherence tomography at baseline and every 3 months after the surgery.

Results: At 12 months after surgery, the retinal reattachment rates was 59.8% (52 eyes) in group A, which was significantly lower than group B (79 eyes, 74.5%; P = 0.029). Logistic regression showed that PPV (P<0.001) and low height of retinal detachment at baseline (P = 0.068) were associated with a greater retinal reattachment rate. Subgroup analysis revealed that in group B, concomitant internal limiting membrane (ILM) peeling showed a slightly higher anatomic success rate (79.2%) than no ILM peeling (70.0%). The postoperative best-corrected visual acuity of the eyes with attached retina between group A and B was not significantly different (P>0.05).

Conclusions: Pars plana vitrectomy with C3F8 endotamponade resulted in a higher anatomic success rate than intravitreal C3F8 gas injection alone in treating retinal detachment owing to macular hole in high myopes.

Financial Disclosure(s): The authors have no proprietary or commercial interest in any materials discussed in the article. Ophthalmology 2009;116:1182-1187 (C) 2009 by the American Academy of Ophthalmology.

语种英语
所属项目编号2004BA720A14 ; 2005CB724307
资助者National "10th five-year plan" of Key Technologies RD Programme ; National Basic Research Program of China ; National "10th five-year plan" of Key Technologies RD Programme ; National Basic Research Program of China
WOS记录号WOS:000266906500022
引用统计
被引频次:27[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/62101
专题北京大学第二临床医学院_眼科
作者单位1.Peking Univ, Peoples Hosp, Dept Ophthalmol, Beijing 100044, Peoples R China
2.Eye Ear Nose Throat Hosp, Dept Ocular Fundus, Shanghai, Peoples R China
3.Sun Yat Sen Univ, Zhong Shan Ophthalm Ctr, Guangzhou 510275, Guangdong, Peoples R China
4.Peking Union Hosp, Peking Union Med Coll, Inst Eye, Beijing, Peoples R China
推荐引用方式
GB/T 7714
Li, Xiaoxin,Wang, Wenji,Tang, Shibo,et al. Gas Injection versus Vitrectomy with Gas for Treating Retinal Detachment Owing to Macular Hole in High Myopes[J]. OPHTHALMOLOGY,2009,116(6):1182-1187.
APA Li, Xiaoxin,Wang, Wenji,Tang, Shibo,&Zhao, Jialiang.(2009).Gas Injection versus Vitrectomy with Gas for Treating Retinal Detachment Owing to Macular Hole in High Myopes.OPHTHALMOLOGY,116(6),1182-1187.
MLA Li, Xiaoxin,et al."Gas Injection versus Vitrectomy with Gas for Treating Retinal Detachment Owing to Macular Hole in High Myopes".OPHTHALMOLOGY 116.6(2009):1182-1187.
条目包含的文件
条目无相关文件。
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Li, Xiaoxin]的文章
[Wang, Wenji]的文章
[Tang, Shibo]的文章
百度学术
百度学术中相似的文章
[Li, Xiaoxin]的文章
[Wang, Wenji]的文章
[Tang, Shibo]的文章
必应学术
必应学术中相似的文章
[Li, Xiaoxin]的文章
[Wang, Wenji]的文章
[Tang, Shibo]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。