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学科主题: 临床医学
题名:
Langerhans cell histiocytosis of the atlas in an adult
作者: Zhong, Wo Quan1; Jiang, Liang1; Ma, Qing Jun1; Liu, Zhong Jun1; Liu, Xiao Guang1; Wei, Feng1; Yuan, Hui Shu2; Dang, Geng Ting1
关键词: Langerhans cell histiocytosis ; Eosinophilic granuloma ; Spine
刊名: EUROPEAN SPINE JOURNAL
发表日期: 2010
DOI: 10.1007/s00586-009-1172-9
卷: 19, 期:1, 页:19-22
收录类别: SCI
文章类型: Editorial Material
WOS标题词: Science & Technology
类目[WOS]: Clinical Neurology ; Orthopedics
研究领域[WOS]: Neurosciences & Neurology ; Orthopedics
关键词[WOS]: TERM-FOLLOW-UP ; EOSINOPHILIC GRANULOMA ; CERVICAL-SPINE ; CHILDREN
英文摘要:

Langerhans cell histiocytosis (LCH), formerly known as histiocytosis X, is a rare disorder (approximately 1:1,500,000 inhabitants) characterized by clonal proliferation and excess accumulation of pathologic Langerhans cells causing local or systemic effects. The exact etiology of LCH is still unknown. LCH could affect patients of any age, although most present when they are children. The most frequent sites of the bony lesions are the skull, femur, mandible, pelvis and spine. A variety of treatment modalities has been reported, but there was no evidence suggesting that any one treatment was more advantageous than another. We present an adult with LCH of the atlas. A 26-year-old young man presented with a 2-month history of neck pain and stiffness. CT revealed osteolytic lesion in the left lateral mass of atlas with compression fracture. Histopathological diagnosis was Langerhans cell histiocytosis by percutaneous needle biopsy under CT guidance. The patient underwent conservative treatment, including Halo-vest immobilization and radiotherapy. At 7-year follow-up, the patient was asymptomatic except for mild motion restriction of the neck. CT revealed a significant reconstruction of the C1 lateral mass.

语种: 英语
WOS记录号: WOS:000273590100003
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/62135
Appears in Collections:北京大学第三临床医学院_骨科_期刊论文

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作者单位: 1.Peking Univ, Dept Orthopaed, Hosp 3, Beijing 100191, Peoples R China
2.Peking Univ, Dept Radiol, Hosp 3, Beijing 100191, Peoples R China

Recommended Citation:
Zhong, Wo Quan,Jiang, Liang,Ma, Qing Jun,et al. Langerhans cell histiocytosis of the atlas in an adult[J]. EUROPEAN SPINE JOURNAL,2010,19(1):19-22.
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