IR@PKUHSC  > 北京大学基础医学院  > 心血管所
学科主题基础医学
Biomedical modification of poly(L-lactide) by blending with lecithin
Zhu, N.; Cui, F. Z.; Hu, K.; Zhu, L.
关键词poly(L-lactide) lecithin film smooth muscle cells tissue engineering
刊名JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
2007-08-01
DOI10.1002/jbm.a.31159
82A期:2页:455-461
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Engineering, Biomedical ; Materials Science, Biomaterials
研究领域[WOS]Engineering ; Materials Science
关键词[WOS]HUMAN-ENDOTHELIAL CELLS ; IN-VITRO ; MECHANICAL-PROPERTIES ; ACID) ; CHONDROCYTES ; DEGRADATION ; CARTILAGE ; VIVO ; CRYSTALLIZATION ; WETTABILITY
英文摘要

Lecithin was, for the first time, blended with PLLA to prepare scaffold material for tissue engineering applications in the present study. Solution blending was used to incorporate Lecithin (containing 0-10 wt %) with PLLA to enhance the blend films biocompatibility, hydrophilicity and toughness while maintaining mechanical strength of PLLA. The results of FTIR-ATR analysis indicated that the amino groups of lecitin existed in the films. DSC analysis indicated that T, decreased with the increase of lecithin content in the blend films. The percentage elongation markedly increased with increase of lecithin content. The proliferation and viability of the vascular smooth muscle cell cultures on PLLA/Lecithin (containing 3-7 wt %) films were significantly enhanced compared to pure PLLA on tissue culture plates. (c) 2007 Wiley Periodicals, Inc.

语种英语
WOS记录号WOS:000247836600021
Citation statistics
Cited Times:16[WOS]   [WOS Record]     [Related Records in WOS]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/62168
Collection北京大学基础医学院_心血管所
作者单位1.Tsing Hua Univ, Dept Mat Sci & Engn, Adv Mat Lab, Beijing 100084, Peoples R China
2.Peking Univ, Hlth Sci Ctr, Inst Cardiovasc Sci, Beijing 100083, Peoples R China
Recommended Citation
GB/T 7714
Zhu, N.,Cui, F. Z.,Hu, K.,et al. Biomedical modification of poly(L-lactide) by blending with lecithin[J]. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A,2007,82A(2):455-461.
APA Zhu, N.,Cui, F. Z.,Hu, K.,&Zhu, L..(2007).Biomedical modification of poly(L-lactide) by blending with lecithin.JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A,82A(2),455-461.
MLA Zhu, N.,et al."Biomedical modification of poly(L-lactide) by blending with lecithin".JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A 82A.2(2007):455-461.
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