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Assessment of the hypoxic-ischemic encephalopathy in neonates using non-invasive near-infrared spectroscopy
Huang, L; Ding, H; Hou, XL; Zhou, CL; Wang, GZ; Tian, FH
关键词near-infrared spectroscopy cerebral oxygenation infant inhaling oxygen stimulation
刊名PHYSIOLOGICAL MEASUREMENT
2004-06-01
DOI10.1088/0967-3334/25/3/014
25期:3页:749-761
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Biophysics ; Engineering, Biomedical ; Physiology
研究领域[WOS]Biophysics ; Engineering ; Physiology
关键词[WOS]CEREBRAL BLOOD-FLOW ; OXYGEN-SATURATION ; NEWBORN-INFANTS ; TISSUE OXYGENATION ; VENOUS OCCLUSION ; CARDIAC-SURGERY ; PRETERM INFANTS ; TERM NEWBORN ; NIRO 300 ; OXIMETRY
英文摘要

This paper introduces a method of monitoring cerebral oxygenation for healthy neonates and neonates with hypoxic-ischemic encephalopathy (HIE) using near-infrared spectroscopy. The object of this study was to investigate whether or not there were differences between the HIE group and the healthy group in terms of NIRS parameters. The subjects were all term neonates, their age ranging from 2 to 18 days. The healthy group included 25 subjects while the HIE group consisted of 16 patients. A prototype NIRS instrument, which provides the data of tissue oxygenation including regional oxygen saturation (602), the increment of oxyhemoglobin concentration and hemoglobin (DeltaHbO(2) and DeltaHb) was used, and the data of rSO(2) was compared with the data from the blood gas analyzer. The result shows that: (1) the mean +/- SD of rSO(2), for the healthy group was 62 +/- 4% in the frontal region under the quiet sleep condition, but the mean +/- SD of rSO(2) for the HIE group was 53 3%. (2) As all subjects inhaled pure oxygen in 21 min(-1) for a period of 60 s, rSO(2) for the healthy group increased rapidly, with the increase in rSO(2) (DeltarSO(2)) being 7 +/- 2.3%, but the increase in rSO(2) for the HIE neonates was 3 +/-1.5%. After inhaling oxygen, DeltaHbO(2) and DeltaHb between the two groups were also significantly different. (3) During all the experiments SpO(2) was monitored, the value of SpO(2) was not significantly different between the two groups. The above observations suggest that the rSO(2) in quiet condition and the values of change of rSO(2), HbO(2), and Hb during the inhalation of oxygen may be used as the parameters to discover and assess the HIE infants.

语种英语
WOS记录号WOS:000222377900015
引用统计
被引频次:23[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/62188
专题北京大学第一临床医学院_儿科
作者单位1.Tsing Hua Univ, Dept Biomed Engn, Beijing 100084, Peoples R China
2.Peking Univ, Teaching Hosp 1, Dept Pediat, Beijing 100034, Peoples R China
推荐引用方式
GB/T 7714
Huang, L,Ding, H,Hou, XL,et al. Assessment of the hypoxic-ischemic encephalopathy in neonates using non-invasive near-infrared spectroscopy[J]. PHYSIOLOGICAL MEASUREMENT,2004,25(3):749-761.
APA Huang, L,Ding, H,Hou, XL,Zhou, CL,Wang, GZ,&Tian, FH.(2004).Assessment of the hypoxic-ischemic encephalopathy in neonates using non-invasive near-infrared spectroscopy.PHYSIOLOGICAL MEASUREMENT,25(3),749-761.
MLA Huang, L,et al."Assessment of the hypoxic-ischemic encephalopathy in neonates using non-invasive near-infrared spectroscopy".PHYSIOLOGICAL MEASUREMENT 25.3(2004):749-761.
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