北京大学医学部机构知识库
Advanced  
IR@PKUHSC  > 基础医学院  > 病原生物学系  > 期刊论文
学科主题: 基础医学
题名:
Hepatitis E Virus Infection among Animals and Humans in Xinjiang, China: Possibility of Swine to Human Transmission of Sporadic Hepatitis E in an Endemic Area
作者: Fu, Hongwei1; Li, Lingjun1; Zhu, Yonghong1; Wang, Ling1; Geng, Jiabao1; Chang, Yibin1; Xue, Cheng2; Du, Gang3; Li, Yaning3; Zhuang, Hui1
刊名: AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
发表日期: 2010-05-01
DOI: 10.4269/ajtmh.2010.09.0689
卷: 82, 期:5, 页:961-966
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Public, Environmental & Occupational Health ; Tropical Medicine
研究领域[WOS]: Public, Environmental & Occupational Health ; Tropical Medicine
关键词[WOS]: GENOME NUCLEOTIDE-SEQUENCE ; EASTERN CHINA ; GENETIC DIVERSITY ; DOMESTIC-ANIMALS ; WILD RATS ; HEV ; IDENTIFICATION ; PREVALENCE ; ANTIBODIES ; GENOTYPE
英文摘要:

Hepatitis E is a worldwide public health problem, especially in areas with poor Sanitation. This study examines the potential hepatitis E virus (HEV) animal reservoirs and the current status of HEV infection among animals and humans in an endemic area of Xinjiang, China. One thousand five hundred twenty-one serum samples from 12 different animal species and 296 sera from humans were detected for anti-HEV with an in-house enzyme immunoassay, and partial HEV RNA was amplified with a reverse transcription nested polymerase chain reaction (RT-nPCR). All these distinct animal species, except jerboa and hoptoad, were positive for anti-HEV. However, HEN RNA was only amplified from pigs and a sporadic hepatitis E case in humans. The human HEV strain (CHN-XJ-HE29) shared 100% nucleotide identity with the swine HEV strain (CHN-XJ-SW50). both of which were collected from the same district: this indicates the possibility of HEV transmission from swine to humans in an endemic area.

语种: 英语
所属项目编号: 30570063 ; 2006A A02Z453
项目资助者: National Natural Science Foundation of China ; 863 National High Technology Research and Development Program of China
WOS记录号: WOS:000277406500034
Citation statistics:
内容类型: 期刊论文
版本: 出版稿
URI标识: http://ir.bjmu.edu.cn/handle/400002259/62192
Appears in Collections:基础医学院_病原生物学系_期刊论文

Files in This Item:
File Name/ File Size Content Type Version Access License
Hepatitis E Virus Infection among Animals and Humans in Xinjiang, China Possibility of Swine to Human Transmission of Sporadic Hepatitis E in an Endemic Area.pdf(679KB)期刊论文出版稿限制开放 联系获取全文

作者单位: 1.Peoples Hosp Qiemo Cty, Clin Lab, Qiemo, Xinjiang Uighur, Peoples R China
2.Cent Hosp Kelamayi, Clin Lab, Kelamayi, Xinjiang Uigher, Peoples R China
3.Peking Univ, Hlth Sci Ctr, Dept Microbiol, Beijing 100191, Peoples R China

Recommended Citation:
Fu, Hongwei,Li, Lingjun,Zhu, Yonghong,et al. Hepatitis E Virus Infection among Animals and Humans in Xinjiang, China: Possibility of Swine to Human Transmission of Sporadic Hepatitis E in an Endemic Area[J]. AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE,2010,82(5):961-966.
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[Fu, Hongwei]'s Articles
[Li, Lingjun]'s Articles
[Zhu, Yonghong]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[Fu, Hongwei]‘s Articles
[Li, Lingjun]‘s Articles
[Zhu, Yonghong]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Copyright © 2007-2017  北京大学医学部 - Feedback
Powered by CSpace