北京大学医学部机构知识库
Advanced  
IR@PKUHSC  > 基础医学院  > 病理学系  > 期刊论文
学科主题: 基础医学
题名:
Psammoma bodies in two types of human ovarian tumours: a mineralogical study (vol 109, pg 357, 2015)
作者: Meng, Fanlu1; Wang, Changqiu1; Li, Yan1; Lu, Anhuai1; Mei, Fang2; Liu, Jianying2; Du, Jingyun3; Zhang, Yan1
刊名: MINERALOGY AND PETROLOGY
发表日期: 2015-06-01
DOI: 10.1007/s00710-015-0381-7
卷: 109, 期:3, 页:367-375
收录类别: SCI
文章类型: Correction
WOS标题词: Science & Technology
类目[WOS]: Geochemistry & Geophysics ; Mineralogy
研究领域[WOS]: Geochemistry & Geophysics ; Mineralogy
关键词[WOS]: CANCER ; COLLAGEN ; NANOBACTERIA ; NUCLEATION ; CRYSTAL ; SITES ; BODY
英文摘要:

Psammoma body (PB) is a common form of calcification in pathological diagnosis and closely relevant to tumours. This paper focuses on the mineralogical characteristics of PBs in ovarian serous cancer and teratoma by using polarization microscope (POM), environmental scanning electron microscope (ESEM), micro-Fourier transform infrared spectroscopy (micro-FT-IR), transmission electron microscope (TEM), micro-area synchrotron radiation X-ray powder diffraction (mu-SRXRD) and fluorescence (mu-SRXRF). Both the PBs in tissues and separated from eight typical cases were investigated. POM and ESEM observation revealed the inside-out growth pattern of PBs. mu-SRXRD and micro-FT-IR results demonstrated the dominant mineral phase of PBs in ovarian serous cancer and teratoma was AB-type carbonate hydroxyapatite (Ca-10[(PO4)(6-x-y)(CO3)(x)(HPO4)(y)][(OH)(2-u)(CO3)(u)] with 0 a parts per thousand currency signaEuro parts per thousand x,y,u a parts per thousand currency signaEuro parts per thousand 2). As observed by ESEM and TEM, the layer-rich PBs in teratoma were up to 70 mu m and mainly consisted of 5 nm-wide, 5-12 nm-long columnar crystals; the PBs in ovarian serous cancer with a maximum diameter of 35 mu m were composed of slightly longer columnar crystals and granulates with 20-100 nm in diameter. The selected area electron diffraction patterns showed dispersed polycrystalline diffraction rings with arching behavior of (002) diffraction, indicating the aggregated nanocrystals grew in the preferred orientation of (002) face. The EDX and mu-SRXRF results together indicated the existence of Na, Mg, Zn and Sr in PBs. These detailed mineralogical characteristics may help uncover the nature of the pathological PBs in ovary.

语种: 英语
WOS记录号: WOS:000355220800011
Citation statistics:
内容类型: 期刊论文
版本: 出版稿
URI标识: http://ir.bjmu.edu.cn/handle/400002259/62247
Appears in Collections:基础医学院_病理学系_期刊论文

Files in This Item:
File Name/ File Size Content Type Version Access License
Psammoma bodies in two types of human ovarian tumours a mineralogical study.pdf(1829KB)期刊论文出版稿限制开放 联系获取全文

作者单位: 1.Peking Univ, Sch Earth & Space Sci, Key Lab Orogen Belts & Crustal Evolut, Beijing 100871, Peoples R China
2.Peking Univ, Sch Basic Med Sci, Dept Pathol, Beijing 100871, Peoples R China
3.Chaihu Hlth Ctr Zhongxiang, Dept Pathol, Zhongxiang, Hubei, Peoples R China

Recommended Citation:
Meng, Fanlu,Wang, Changqiu,Li, Yan,et al. Psammoma bodies in two types of human ovarian tumours: a mineralogical study (vol 109, pg 357, 2015)[J]. MINERALOGY AND PETROLOGY,2015,109(3):367-375.
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[Meng, Fanlu]'s Articles
[Wang, Changqiu]'s Articles
[Li, Yan]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[Meng, Fanlu]‘s Articles
[Wang, Changqiu]‘s Articles
[Li, Yan]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit
所有评论 (0)
暂无评论
 
评注功能仅针对注册用户开放,请您登录
您对该条目有什么异议,请填写以下表单,管理员会尽快联系您。
内 容:
Email:  *
单位:
验证码:   刷新
您在IR的使用过程中有什么好的想法或者建议可以反馈给我们。
标 题:
 *
内 容:
Email:  *
验证码:   刷新

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Copyright © 2007-2017  北京大学医学部 - Feedback
Powered by CSpace