|Association Between Periodontitis and Chronic Obstructive Pulmonary Disease in a Chinese Population|
|Si, Yan2; Fan, Hong3; Song, Yiqing4; Zhou, Xuan1; Zhang, Jing1; Wang, Zuomin1|
|关键词||Periodontitis pulmonary disease chronic obstructive respiratory function tests|
|刊名||JOURNAL OF PERIODONTOLOGY|
|WOS标题词||Science & Technology|
|类目[WOS]||Dentistry, Oral Surgery & Medicine|
|研究领域[WOS]||Dentistry, Oral Surgery & Medicine|
|关键词[WOS]||C-REACTIVE PROTEIN ; BODE INDEX ; AIRWAY-OBSTRUCTION ; COPD ; INFECTIONS ; DYSPNEA ; PREDICTORS ; MORTALITY ; SURVIVAL ; HEALTH|
Background: A relationship between periodontitis and chronic respiratory disease has been suggested by recent studies. The aim of this study is to explore the association between periodontitis and chronic obstructive pulmonary disease (COPD) in a Chinese population.
Methods: We conducted a case-control study of 581 COPD cases and 438 non-COPD controls. Lung function examination, a 6-minute walk test, and the British Medical Research Council questionnaire were performed. Periodontal clinical examination index included probing depth (PD), attachment loss (AL), bleeding index (BI), plaque index (PI), and alveolar bone loss. A validated index for predicting COPD prognosis, the body mass index, airflow obstruction, dyspnea, and exercise capacity (BODE) index, was also calculated.
Results: Participants with more severe COPD were more likely to have severe periodontal disease. PD, AL, PI, alveolar bone loss, and the number of teeth were significantly associated with all stages of COPD (all P<0.001). When compared to controls (BODE=0), participants with higher BODE scores had significantly higher AL (P <0.001), BI (P = 0.027), PI (P<0.001), alveolar bone loss (P<0.001), and the number of teeth (P <0.001). PI appeared to be the main periodontal health-related factor for COPD, with an odds ratio (OR) = 9.01 (95% CI = 3.98 to 20.4) in the entire study population OR = 8.28 (95% CI = 2.36 to 29.0), OR = 5.89 (95% CI = 2.64 to 13.1), and OR = 2.46 (95% CI = 1.47 to 4.10) for current, smokers, and non-smokers, respectively.
Conclusion: Our study found a strong association between periodontitis and COPD, and PI seemed to be a major periodontal factor for predicting COPD among Chinese adults. J Periodontol 2012;83:1288-1296.
|资助机构||Beijing Municipal Science and Technology Commission (Beijing, China) ; National Natural Science Foundation of China ; Beijing ChaoYang Hospital|
|作者单位||1.Shanxi Peoples Hosp, Dept Stomatol, Shanxi, Peoples R China|
2.Capital Med Univ, Beijing ChaoYang Hosp, Dept Stomatol, Beijing, Peoples R China
3.Peking Univ, Dept Prevent Dent, Sch & Hosp Stomatol, Beijing 100871, Peoples R China
4.Harvard Univ, Brigham & Womens Hosp, Sch Med, Div Prevent Med, Boston, MA 02115 USA
|Si, Yan,Fan, Hong,Song, Yiqing,et al. Association Between Periodontitis and Chronic Obstructive Pulmonary Disease in a Chinese Population[J]. JOURNAL OF PERIODONTOLOGY,2012,83(10):1288-1296.|
|APA||Si, Yan,Fan, Hong,Song, Yiqing,Zhou, Xuan,Zhang, Jing,&Wang, Zuomin.(2012).Association Between Periodontitis and Chronic Obstructive Pulmonary Disease in a Chinese Population.JOURNAL OF PERIODONTOLOGY,83(10),1288-1296.|
|MLA||Si, Yan,et al."Association Between Periodontitis and Chronic Obstructive Pulmonary Disease in a Chinese Population".JOURNAL OF PERIODONTOLOGY 83.10(2012):1288-1296.|