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学科主题: 口腔医学
题名:
Association Between Periodontitis and Chronic Obstructive Pulmonary Disease in a Chinese Population
作者: Si, Yan2; Fan, Hong3; Song, Yiqing4; Zhou, Xuan1; Zhang, Jing1; Wang, Zuomin1
关键词: Periodontitis ; pulmonary disease ; chronic obstructive ; respiratory function tests
刊名: JOURNAL OF PERIODONTOLOGY
发表日期: 2012-10-01
DOI: 10.1902/jop.2012.110472
卷: 83, 期:10, 页:1288-1296
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Dentistry, Oral Surgery & Medicine
研究领域[WOS]: Dentistry, Oral Surgery & Medicine
关键词[WOS]: C-REACTIVE PROTEIN ; BODE INDEX ; AIRWAY-OBSTRUCTION ; COPD ; INFECTIONS ; DYSPNEA ; PREDICTORS ; MORTALITY ; SURVIVAL ; HEALTH
英文摘要:

Background: A relationship between periodontitis and chronic respiratory disease has been suggested by recent studies. The aim of this study is to explore the association between periodontitis and chronic obstructive pulmonary disease (COPD) in a Chinese population.

Methods: We conducted a case-control study of 581 COPD cases and 438 non-COPD controls. Lung function examination, a 6-minute walk test, and the British Medical Research Council questionnaire were performed. Periodontal clinical examination index included probing depth (PD), attachment loss (AL), bleeding index (BI), plaque index (PI), and alveolar bone loss. A validated index for predicting COPD prognosis, the body mass index, airflow obstruction, dyspnea, and exercise capacity (BODE) index, was also calculated.

Results: Participants with more severe COPD were more likely to have severe periodontal disease. PD, AL, PI, alveolar bone loss, and the number of teeth were significantly associated with all stages of COPD (all P<0.001). When compared to controls (BODE=0), participants with higher BODE scores had significantly higher AL (P <0.001), BI (P = 0.027), PI (P<0.001), alveolar bone loss (P<0.001), and the number of teeth (P <0.001). PI appeared to be the main periodontal health-related factor for COPD, with an odds ratio (OR) = 9.01 (95% CI = 3.98 to 20.4) in the entire study population OR = 8.28 (95% CI = 2.36 to 29.0), OR = 5.89 (95% CI = 2.64 to 13.1), and OR = 2.46 (95% CI = 1.47 to 4.10) for current, smokers, and non-smokers, respectively.

Conclusion: Our study found a strong association between periodontitis and COPD, and PI seemed to be a major periodontal factor for predicting COPD among Chinese adults. J Periodontol 2012;83:1288-1296.

语种: 英语
所属项目编号: 30872878
项目资助者: Beijing Municipal Science and Technology Commission (Beijing, China) ; National Natural Science Foundation of China ; Beijing ChaoYang Hospital
WOS记录号: WOS:000309793800011
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/62268
Appears in Collections:北京大学口腔医学院_口腔预防保健科_期刊论文

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作者单位: 1.Shanxi Peoples Hosp, Dept Stomatol, Shanxi, Peoples R China
2.Capital Med Univ, Beijing ChaoYang Hosp, Dept Stomatol, Beijing, Peoples R China
3.Peking Univ, Dept Prevent Dent, Sch & Hosp Stomatol, Beijing 100871, Peoples R China
4.Harvard Univ, Brigham & Womens Hosp, Sch Med, Div Prevent Med, Boston, MA 02115 USA

Recommended Citation:
Si, Yan,Fan, Hong,Song, Yiqing,et al. Association Between Periodontitis and Chronic Obstructive Pulmonary Disease in a Chinese Population[J]. JOURNAL OF PERIODONTOLOGY,2012,83(10):1288-1296.
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