IR@PKUHSC  > 北京大学药学院  > 天然药物学系
学科主题药学
Three new lignans, longipedunins A-C, from Kadsura longipedunculata and their inhibitory activity against HIV-1 protease
Sun, QZ; Chen, DF; Ding, PL; Ma, CM; Kakuda, H; Nakamura, N; Hattori, M
关键词longipedunin Kadsura longipedunculata HIV-1 protease lignan X-ray crystal structure
刊名CHEMICAL & PHARMACEUTICAL BULLETIN
2006
54期:1页:129-132
收录类别SCI ; IC
文章类型Article
WOS标题词Science & Technology
类目[WOS]Chemistry, Medicinal ; Chemistry, Multidisciplinary ; Pharmacology & Pharmacy
研究领域[WOS]Pharmacology & Pharmacy ; Chemistry
关键词[WOS]DIBENZOCYCLOOCTADIENE LIGNANS ; CONSTITUENTS ; CHINENSIS
英文摘要

Three new lignans, longipedunins A (1), B (2) and C (3), together with three known compounds, benzoyl-binankadsurin A (4), acetyl-binankadsurin A (5) and schisanlactone A (6), were isolated from Kadsura longipedtunculata. Their structures and stereochemistry were determined by spectral and single-crystal X-ray analyses. Compounds 1 and 6 showed appreciable inhibitory activity against HIV-1 protease with IC50 values of 50 and 20 mu M, respectively.

语种英语
WOS记录号WOS:000234790900029
引用统计
被引频次:17[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/62288
专题北京大学药学院_天然药物学系
作者单位1.Toyama Med & Pharmaceut Univ, Chem Lab, Toyama 9300194, Japan
2.Toyama Med & Pharmaceut Univ, Inst Nat Med, Dept Metab Engn, Toyama 9300194, Japan
3.Fudan Univ, Sch Pharm, Dept Pharmacognosy, Shanghai 200032, Peoples R China
4.Peking Univ, Sch Pharmaceut Sci, Dept Nat Med, Beijing 100083, Peoples R China
推荐引用方式
GB/T 7714
Sun, QZ,Chen, DF,Ding, PL,et al. Three new lignans, longipedunins A-C, from Kadsura longipedunculata and their inhibitory activity against HIV-1 protease[J]. CHEMICAL & PHARMACEUTICAL BULLETIN,2006,54(1):129-132.
APA Sun, QZ.,Chen, DF.,Ding, PL.,Ma, CM.,Kakuda, H.,...&Hattori, M.(2006).Three new lignans, longipedunins A-C, from Kadsura longipedunculata and their inhibitory activity against HIV-1 protease.CHEMICAL & PHARMACEUTICAL BULLETIN,54(1),129-132.
MLA Sun, QZ,et al."Three new lignans, longipedunins A-C, from Kadsura longipedunculata and their inhibitory activity against HIV-1 protease".CHEMICAL & PHARMACEUTICAL BULLETIN 54.1(2006):129-132.
条目包含的文件
条目无相关文件。
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Sun, QZ]的文章
[Chen, DF]的文章
[Ding, PL]的文章
百度学术
百度学术中相似的文章
[Sun, QZ]的文章
[Chen, DF]的文章
[Ding, PL]的文章
必应学术
必应学术中相似的文章
[Sun, QZ]的文章
[Chen, DF]的文章
[Ding, PL]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。