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学科主题临床医学
Mutual information based three-dimensional registration of rat brain magnetic resonance imaging time-series
Liu, Bo1; Bai, Xiangzhi1,3,4; Zhou, Fugen1; Han, Hongbin2; Hou, Chao2
刊名COMPUTERS & ELECTRICAL ENGINEERING
2013-07-01
DOI10.1016/j.compeleceng.2012.11.026
39期:5页:1473-1484
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Computer Science, Hardware & Architecture ; Computer Science, Interdisciplinary Applications ; Engineering, Electrical & Electronic
研究领域[WOS]Computer Science ; Engineering
关键词[WOS]FREE-FORM DEFORMATIONS ; NONRIGID REGISTRATION ; MR-IMAGES ; RIGIDITY ; SEGMENTATION ; ALIGNMENT ; PENALTY
英文摘要

An efficient mutual information (MI) based automatic registration method is introduced to align the rat brain tissues in magnetic resonance imaging (MRI) time-series, which is critical to the MRI tracer method for quantitative analysis of brain extracellular space (ECS). The method is specially designed to address the specific properties of contrast-enhanced MRI time-series. Firstly, a segmentation method is proposed to extract the brain tissue mask which is used in MI computing to avoid the adverse effects of surrounding deformed tissues. Secondly, a two-stage registration framework is proposed, where the images are first aligned using deformable registration and then finally matched by rigid registration. A series of experiments are conducted to evaluate the registration method qualitatively and quantitatively. The experimental results show that the proposed method has a high degree of accuracy and reliability, and is adequate to the task of three-dimensional registration of rat brain MRI time-series. (C) 2012 Elsevier Ltd. All rights reserved.

语种英语
WOS记录号WOS:000322430600009
项目编号30972811 ; 61171005 ; 3102020
资助机构National Natural Science Foundation of China ; Natural Science Foundation of Beijing
引用统计
被引频次:9[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/62358
专题北京大学第三临床医学院_放射科
作者单位1.Beihang Univ, Image Proc Ctr, Beijing 100191, Peoples R China
2.Peking Univ, Hosp 3, Dept Radiol, Beijing 100191, Peoples R China
3.Beihang Univ, State Key Lab Virtual Real Technol & Syst, Beijing 100191, Peoples R China
4.Beihang Univ, Beijing Key Lab Digital Media, Beijing 100191, Peoples R China
推荐引用方式
GB/T 7714
Liu, Bo,Bai, Xiangzhi,Zhou, Fugen,et al. Mutual information based three-dimensional registration of rat brain magnetic resonance imaging time-series[J]. COMPUTERS & ELECTRICAL ENGINEERING,2013,39(5):1473-1484.
APA Liu, Bo,Bai, Xiangzhi,Zhou, Fugen,Han, Hongbin,&Hou, Chao.(2013).Mutual information based three-dimensional registration of rat brain magnetic resonance imaging time-series.COMPUTERS & ELECTRICAL ENGINEERING,39(5),1473-1484.
MLA Liu, Bo,et al."Mutual information based three-dimensional registration of rat brain magnetic resonance imaging time-series".COMPUTERS & ELECTRICAL ENGINEERING 39.5(2013):1473-1484.
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