|Prevalence and Correlates of HIV and HCV Infection Among Amphetamine-Type Stimulant Users in 6 Provinces in China|
|Bao, Yan-Ping1; Liu, Zhi-Min1; Lian, Zhi1; Li, Jian-Hua; Zhang, Rui-Min2; Zhang, Cong-Bin2; Hao, Wei3; Wang, Xu-Yi3; Zhao, Min4; Jiang, Hai-Feng4; Yan, Shi-Yan1; Wang, Qing-Liang1; Qu, Zhi1; Zhang, Hao-Ran1; Wu, Ping1; Shi, Jie1; Lu, Lin1|
|关键词||amphetamine-type stimulant HIV HCV risk factor China|
|刊名||JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES|
|WOS标题词||Science & Technology|
|类目[WOS]||Immunology ; Infectious Diseases|
|研究领域[WOS]||Immunology ; Infectious Diseases|
|关键词[WOS]||HEPATITIS-C VIRUS ; SEXUALLY-TRANSMITTED INFECTIONS ; METHAMPHETAMINE USERS ; RISK BEHAVIOR ; PHNOM-PENH ; DRUG-USERS ; SEX ; TRANSMISSION ; EPIDEMIC ; THAILAND|
Background: China has experienced an epidemic of amphetamine-type stimulant (ATS) use in recent years. The present study explored the status and correlates of HIV and hepatitis C virus (HCV) infection among ATS users in China.
Methods: A multicenter cross-sectional study of HIV and HCV status and associated behaviors among ATS users was conducted in 6 provinces from September 2009 to December 2010. Socioeconomic/behavioral risk factors were measured. Blood samples were collected to test for HIV and HCV antibodies.
Results: Of the 1327 ATS users, the prevalence of HIV and exposure to HCV were 4.5% and 43.5%, respectively, with large geographic variations (0%-20.3% and 8.6%-67.1%, respectively). HIV infection was independently associated with living in Yunnan province [adjusted odds ratio = 15.8; 95% confidence interval (CI): 2.0 to 125.1), polydrug use (adjusted odds ratio = 2.6; 95% CI: 1.3 to 5.4), increased frequency of sexual behavior (adjusted odds ratio = 2.0; 95% CI: 1.1 to 4.1), history of sex with sexually transmitted infection-positive persons (adjusted odds ratio = 11.4; 95% CI: 1.3 to 98.9), and HCV infection (adjusted odds ratio = 2.8; 95% CI: 1.2 to 6.7). HCV was associated with study site, marital status, unemployment (adjusted odds ratio = 1.8; 95% CI: 1.3 to 2.4), a longer duration of ATS use, and history of injection use of ATS (adjusted odds ratio = 13.3; 95% CI: 1.5 to 116.1).
Conclusions: The prevalence of HIV was high among ATS users in Yunnan province but quite rare elsewhere, and the prevalence of exposure to HCV was high in 6 provinces. Risk factors emphasize the need for new prevention strategies toward this population at risk in China.
|项目编号||2008ZX10001-003 ; 2012ZX10001001 ; 2009CB522007 ; 81001265|
|资助机构||Chinese Ministry of Science and Technology ; National Basic Research Program of China ; National Natural Science Foundation of China|
|作者单位||1.Peking Univ, Natl Inst Drug Dependence, Beijing 100191, Peoples R China|
2.Yunnan Inst Drug Abuse, Kunming, Yunnan, Peoples R China
3.Cent S Univ, Mental Hlth Inst, Xiangya Hosp 2, Changsha, Hunan, Peoples R China
4.Shanghai Jiao Tong Univ, Shanghai Mental Hlth Ctr, Sch Med, Shanghai 200030, Peoples R China
|Bao, Yan-Ping,Liu, Zhi-Min,Lian, Zhi,et al. Prevalence and Correlates of HIV and HCV Infection Among Amphetamine-Type Stimulant Users in 6 Provinces in China[J]. JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES,2012,60(4):438-446.|
|APA||Bao, Yan-Ping.,Liu, Zhi-Min.,Lian, Zhi.,Li, Jian-Hua.,Zhang, Rui-Min.,...&Lu, Lin.(2012).Prevalence and Correlates of HIV and HCV Infection Among Amphetamine-Type Stimulant Users in 6 Provinces in China.JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES,60(4),438-446.|
|MLA||Bao, Yan-Ping,et al."Prevalence and Correlates of HIV and HCV Infection Among Amphetamine-Type Stimulant Users in 6 Provinces in China".JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES 60.4(2012):438-446.|