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学科主题: 药物依赖
题名:
Prevalence and Correlates of HIV and HCV Infection Among Amphetamine-Type Stimulant Users in 6 Provinces in China
作者: Bao, Yan-Ping1; Liu, Zhi-Min1; Lian, Zhi1; Li, Jian-Hua; Zhang, Rui-Min2; Zhang, Cong-Bin2; Hao, Wei3; Wang, Xu-Yi3; Zhao, Min4; Jiang, Hai-Feng4; Yan, Shi-Yan1; Wang, Qing-Liang1; Qu, Zhi1; Zhang, Hao-Ran1; Wu, Ping1; Shi, Jie1; Lu, Lin1
关键词: amphetamine-type stimulant ; HIV ; HCV ; risk factor ; China
刊名: JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES
发表日期: 2012-08-01
DOI: 10.1097/QAI.0b013e31825694f2
卷: 60, 期:4, 页:438-446
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Immunology ; Infectious Diseases
研究领域[WOS]: Immunology ; Infectious Diseases
关键词[WOS]: HEPATITIS-C VIRUS ; SEXUALLY-TRANSMITTED INFECTIONS ; METHAMPHETAMINE USERS ; RISK BEHAVIOR ; PHNOM-PENH ; DRUG-USERS ; SEX ; TRANSMISSION ; EPIDEMIC ; THAILAND
英文摘要:

Background: China has experienced an epidemic of amphetamine-type stimulant (ATS) use in recent years. The present study explored the status and correlates of HIV and hepatitis C virus (HCV) infection among ATS users in China.

Methods: A multicenter cross-sectional study of HIV and HCV status and associated behaviors among ATS users was conducted in 6 provinces from September 2009 to December 2010. Socioeconomic/behavioral risk factors were measured. Blood samples were collected to test for HIV and HCV antibodies.

Results: Of the 1327 ATS users, the prevalence of HIV and exposure to HCV were 4.5% and 43.5%, respectively, with large geographic variations (0%-20.3% and 8.6%-67.1%, respectively). HIV infection was independently associated with living in Yunnan province [adjusted odds ratio = 15.8; 95% confidence interval (CI): 2.0 to 125.1), polydrug use (adjusted odds ratio = 2.6; 95% CI: 1.3 to 5.4), increased frequency of sexual behavior (adjusted odds ratio = 2.0; 95% CI: 1.1 to 4.1), history of sex with sexually transmitted infection-positive persons (adjusted odds ratio = 11.4; 95% CI: 1.3 to 98.9), and HCV infection (adjusted odds ratio = 2.8; 95% CI: 1.2 to 6.7). HCV was associated with study site, marital status, unemployment (adjusted odds ratio = 1.8; 95% CI: 1.3 to 2.4), a longer duration of ATS use, and history of injection use of ATS (adjusted odds ratio = 13.3; 95% CI: 1.5 to 116.1).

Conclusions: The prevalence of HIV was high among ATS users in Yunnan province but quite rare elsewhere, and the prevalence of exposure to HCV was high in 6 provinces. Risk factors emphasize the need for new prevention strategies toward this population at risk in China.

语种: 英语
所属项目编号: 2008ZX10001-003 ; 2012ZX10001001 ; 2009CB522007 ; 81001265
项目资助者: Chinese Ministry of Science and Technology ; National Basic Research Program of China ; National Natural Science Foundation of China
WOS记录号: WOS:000306242300020
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/62457
Appears in Collections:中国药物依赖性研究所_期刊论文

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作者单位: 1.Peking Univ, Natl Inst Drug Dependence, Beijing 100191, Peoples R China
2.Yunnan Inst Drug Abuse, Kunming, Yunnan, Peoples R China
3.Cent S Univ, Mental Hlth Inst, Xiangya Hosp 2, Changsha, Hunan, Peoples R China
4.Shanghai Jiao Tong Univ, Shanghai Mental Hlth Ctr, Sch Med, Shanghai 200030, Peoples R China

Recommended Citation:
Bao, Yan-Ping,Liu, Zhi-Min,Lian, Zhi,et al. Prevalence and Correlates of HIV and HCV Infection Among Amphetamine-Type Stimulant Users in 6 Provinces in China[J]. JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES,2012,60(4):438-446.
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