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学科主题: 药学
题名:
Traditional Chinese patent medicines for cancer treatment in China: a nationwide medical insurance data analysis
作者: Wu, Min1; Lu, Peng4; Shi, Luwen1; Li, Shao2,3
关键词: traditional Chinese medicine ; cancer treatment ; medical insurance ; nationwide survey ; herb-drug network
刊名: ONCOTARGET
发表日期: 2015-11-10
卷: 6, 期:35, 页:38283-38295
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Oncology ; Cell Biology
研究领域[WOS]: Oncology ; Cell Biology
关键词[WOS]: HERBAL FORMULAS ; ASTRAGALI-RADIX ; MATRINE ; CELLS
英文摘要:

Based on the nationwide survey into inpatients′ utilization of the health service covered by China′s urban basic medical insurance from 2008 to 2010, we analyzed the use rate, cancer profile and combined use of anticancer Chinese patent medicines (CPMs) on 51,382 insured cancer patients by using statistical, bi-clustering and network methods. We found that 42.4% of 51,382 cancer patients used 33 anticancer CPMs, and 51.7% used 71 anticancer Western medicines (WMs). The CPMs were most often used in lung (52%) and nasopharynx (52%) cancer patients, and least in bladder cancer (21%) and leukemia of unspecified cell type (21%) patients. The cost per patient for all 33 anticancer CPMs was 2069RMB, lower than that of the WMs (3458RMB). The cancer profile of commonly used CPMs and WMs for the top 17 cancers (>500 sampled patients) were provided, indicating anticancer CPMs had a broad spectrum of cancers and lacked selectivity in cancer treatment (CPM mean CV = 49%; WM mean CV = 152%). Moreover, 24.8% of the cancer patients used both CPMs and WMs, and CPM-WM combined use networks were constructed for four major cancers. This first nationwide analysis revealed the use characteristics and herb-drug combined use patterns of insurance covered anticancer CPMs in China. The study offers valuable information to guide future studies of the precision, safety and standard use of CPMs.

语种: 英语
所属项目编号: 81225025 ; 91229201
项目资助者: National Natural Science Foundation of China
WOS记录号: WOS:000366113200096
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/62465
Appears in Collections:北京大学药学院_期刊论文

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作者单位: 1.Chinese Acad Sci, Inst Automat, Beijing, Peoples R China
2.Peking Univ, Sch Pharmaceut Sci, Dept Pharm Adm & Clin Pharm, Beijing 100871, Peoples R China
3.Tsinghua Univ, Dept Automat, TNLIST, MOE Key Lab Bioinformat, Beijing 100084, Peoples R China
4.Tsinghua Univ, Dept Automat, TNLIST, Bioinformat Div, Beijing 100084, Peoples R China

Recommended Citation:
Wu, Min,Lu, Peng,Shi, Luwen,et al. Traditional Chinese patent medicines for cancer treatment in China: a nationwide medical insurance data analysis[J]. ONCOTARGET,2015,6(35):38283-38295.
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