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Investigation of Two Flacourtiaceae Plants: Bennettiodendron leprosipes and Flacourtia ramontchi
Chai, Xing-Yun1; Ren, Hong-Yan1; Xu, Zheng-Ren1; Bai, Chang-Cai1; Zhou, Fei-Ran1; Ling, Si-Kai2; Pu, Xiao-Ping2; Li, Fei-Fei1; Tu, Peng-Fei1
关键词Bennettiodendron leprosipes Flacourtia ramontchi benosides A and B bennettin, flacosides A-C phosphodiesterase I Flacourtiaceae
刊名PLANTA MEDICA
2009-09-01
DOI10.1055/s-0029-1185542
75期:11页:1246-1252
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
研究领域[WOS]Plant Sciences ; Pharmacology & Pharmacy
关键词[WOS]WATER-SOLUBLE CONSTITUENTS ; PHENOLIC GLYCOSIDES ; MEGASTIGMANE GLYCOSIDES ; DERIVATIVES ; ALCOHOL ; GLUCOSIDES ; INHIBITORS ; LIGNANS ; STEMS
英文摘要

Investigations of two Flacourtiaceae plants, Bennettiodendron leprosipes and Flacourtia ramontchi, resulted in the isolation and structural elucidation of six new constituents including two phenolic glycosides (1 and 2), one lignan (3), two lignan glycosides (4 and 5), and a monoterpene glycoside (6), together with 22 known compounds (7-28). The structures of the new compounds were elucidated by spectroscopic analysis and chemical methods. The selected isolates 1, 2, 8-10, 22-26, and some phenolic glycosides 29-42 previously isolated from another Flacourtiaceae plant, Itoa orientalis, were tested against snake venom phosphodiesterase I (PIDE I) activity. The result indicated that 22, 30, 32, 34, and 40 exhibited moderate inhibitory activities against PDE I with the values ranging from 13.15 to 20.86%, and 1, 8,10, 25, 31, 33, 35, 38, 39, and 41 showed weak inhibitory activity.

语种英语
WOS记录号WOS:000270401600013
引用统计
被引频次:11[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/62480
专题北京大学药学院
北京大学医学部管理机构_医学部
北京大学药学院_天然药物学系
北京大学药学院_分子与细胞药理学系
作者单位1.Peking Univ, Hlth Sci Ctr, State Key Lab Nat & Biomimet Drugs, Sch Pharmaceut Sci, Beijing 100191, Peoples R China
2.Peking Univ, Hlth Sci Ctr, Sch Pharmaceut Sci, Dept Pharmacol, Beijing 100191, Peoples R China
推荐引用方式
GB/T 7714
Chai, Xing-Yun,Ren, Hong-Yan,Xu, Zheng-Ren,et al. Investigation of Two Flacourtiaceae Plants: Bennettiodendron leprosipes and Flacourtia ramontchi[J]. PLANTA MEDICA,2009,75(11):1246-1252.
APA Chai, Xing-Yun.,Ren, Hong-Yan.,Xu, Zheng-Ren.,Bai, Chang-Cai.,Zhou, Fei-Ran.,...&Tu, Peng-Fei.(2009).Investigation of Two Flacourtiaceae Plants: Bennettiodendron leprosipes and Flacourtia ramontchi.PLANTA MEDICA,75(11),1246-1252.
MLA Chai, Xing-Yun,et al."Investigation of Two Flacourtiaceae Plants: Bennettiodendron leprosipes and Flacourtia ramontchi".PLANTA MEDICA 75.11(2009):1246-1252.
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