IR@PKUHSC  > 北京大学第一临床医学院  > 皮肤性病科
学科主题临床医学
Contact Sensitization in Chinese Patients with Hand Eczema
Ni, Chunya1; Dou, Xia; Chen, Jianyou; Zhu, Xuejun; Liu, Lingling
刊名DERMATITIS
2011-07-01
DOI10.2310/6620.2011.10123
22期:4页:211-215
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Dermatology
研究领域[WOS]Dermatology
关键词[WOS]OCCUPATIONAL SKIN-DISEASE ; FRAGRANCE ALLERGY ; NICKEL ALLERGY ; RISK-FACTORS ; POPULATION ; DERMATITIS ; PREVALENCE ; SAMPLE ; MULTICENTER ; INDUSTRY
英文摘要

Background: Contact sensitization is an important cause of hand eczema, a common disease that affects both daily and occupational life.

Objective: To describe contact allergens in Chinese patients with hand eczema and to analyze the association between allergens and occupational exposure.

Methods: Three hundred sixty-six patients with hand eczema underwent patch testing with a modified North American standard series between September 1989 and December 2009.

Results: Positive patch-test reactions were observed in 74% of patients. The most frequent allergens were p-phenylenediamine (22.7%), nickel sulfate (21.9%), fragrance mix (19.9%), ammoniated mercury (19.7%), and carba mix (17.8%). Nickel and fragrance allergy in women, and carba mix and chromate allergy in men, showed gender predilection, and 64.2% of patients developed hand eczema from occupational exposure. Positive reactions to p-phenylenediamine in hairdressers and to chromate in metalworkers and construction workers presented higher frequencies (p < .05).

Conclusions: p-Phenylenediamine, nickel, fragrance, mercury, and rubber chemicals are common allergens in Chinese patients with hand eczema. Gender and occupation may cause different exposures; thus, allergens may vary.

语种英语
WOS记录号WOS:000294387200004
引用统计
被引频次:4[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/62551
专题北京大学第一临床医学院_皮肤性病科
作者单位1.Peking Univ, Dept Dermatol, Hosp 1, Beijing 100871, Peoples R China
2.Fudan Univ, Dept Dermatol, Huashan Hosp, Shanghai 200433, Peoples R China
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GB/T 7714
Ni, Chunya,Dou, Xia,Chen, Jianyou,et al. Contact Sensitization in Chinese Patients with Hand Eczema[J]. DERMATITIS,2011,22(4):211-215.
APA Ni, Chunya,Dou, Xia,Chen, Jianyou,Zhu, Xuejun,&Liu, Lingling.(2011).Contact Sensitization in Chinese Patients with Hand Eczema.DERMATITIS,22(4),211-215.
MLA Ni, Chunya,et al."Contact Sensitization in Chinese Patients with Hand Eczema".DERMATITIS 22.4(2011):211-215.
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